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Penicillins With Antipseudomonal Activity

Published online by Cambridge University Press:  02 January 2015

Sandra M. Norris
Sandra M. Norris*
Affiliation:
Department of Medicine, University of Virginia Medical Center, School of Medicine, Charlottesville, Virginia
*
School of Medicine, University of Virginia, Charlottesville, VA 22908
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Extract

The escalating role of Pseudomonas aeruginosa as a nosocomial pathogen, the relatively high mortality rate associated with pseudomonal infections, the intrinsic antibiotic resistance of this versatile, ubiquitous organism, and the growing number of reports of multiple antibiotic resistance developing during therapy of Pseudomonas infections prompt a review of currently available penicillins with antipseudomonal activity. Ticarcillin, piperacillin, mezlocillin and azlocillin have upstaged carbenicillin, the first antipseudomonal, β-lactam agent clinically used, with other products “in the wings.”

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 6 , Issue 4 , April 1985 , pp. 165 - 168
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1985

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