Hostname: page-component-8448b6f56d-wq2xx Total loading time: 0 Render date: 2024-04-23T10:59:50.833Z Has data issue: false hasContentIssue false

Inappropriate Antibiotic Use in a Tertiary Care Center in Thailand: An Incidence Study and Review of Experience in Thailand

Published online by Cambridge University Press:  21 June 2016

Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases, Thammasart University Hospital, Pratumthani, Thailand
Somwang Danchaivijitr
Affiliation:
Faculty of Medicine, Division of Infectious Diseases, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Thomas C. Bailey
Affiliation:
Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri
Victoria J. Fraser
Affiliation:
Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri
*
Division of Infectious Diseases, Thammasart University Hospital, Pratumthani, Thailand12120 (anapisarn@yahoo.com)

Abstract

The incidence and patterns of and factors associated with inappropriate antibiotic use were studied in a tertiary care center in Thailand. The incidence of inappropriate antibiotic use was 25%. Admission to the surgical department (adjusted odds ratio, 2.0; P = .02) and to the obstetrics and gynecology department (adjusted odds ratio, 2.0; P = .03) were associated with inappropriate antibiotic use, whereas consultation with an infectious diseases specialist was protective against inappropriate antibiotic use (adjusted odds ratio, 0.15; P = .01).

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Belongia, EA, Schwartz, B. Strategies for promoting judicious use of antibiotics by doctors and patients. BMJ 1998; 317:668671.Google Scholar
2.Thamlikitkul, V. Antibiotic dispensing by drug store personnel in Bangkok, Thailand. J Antimicrob Chemother 1988; 21:125131.Google Scholar
3.Srifuengfung, S, Polwichai, P, Champreeda, P, et al. Prevalence of antimicrobial resistance in Streptococcus pneumoniae isolated in Thailand [abstract FP-A-5]. In: Program and abstracts of the 9th Western Pacific Congress on Chemotherapy and Infectious Diseases (Bangkok, Thailand). Kuala Lumpur, Malaysia: Western Pacific Society of Chemotherapy; 2004:187.Google Scholar
4.Dejsirilert, S, Apisarnthanarak, A, Kitphati, R, et al. The status of antimicrobial resistance in Thailand among gram-negative pathogens in bloodstream infections: NARST data, 2000-2003 [abstract FP-A-3]. In: Program and abstracts of the 9th Western Pacific Congress on Chemotherapy and Infectious Diseases (Bangkok, Thailand). Kuala Lumpur, Malaysia: Western Pacific Society of Chemotherapy; 2004:185.Google Scholar
5.Apisarnthanarak, A, Mundy, LM. Prevalence, treatment, and outcome of infection due to extended-spectrum β-lactamase–producing microorganisms. Infect Control Hosp Epidemiol 2006; 27:326327.Google Scholar
6.Kunin, CM, Tupasi, T, Craig, WA. Use of antibiotics: a brief exposition of the problem and some tentative solutions. Ann Intern Med 1973; 79:555560.CrossRefGoogle ScholarPubMed
7.Bratzier, DW, Houch, PM. Antimicrobial prophylaxis for surgery: an advisory statement for the national surgical infection prevention project. Clin Infect Dis 2004; 38:17061715.Google Scholar
8.Udomthavornsuk, B, Tatsanavivat, P, Patjanasoontorn, B, et al. Antibiotic use at a university hospital. Antiobiotic Working Group of Srinagarind Hospital. J Med Assoc Thai 1990; 72:168174.Google Scholar
9.Aswapokee, N, Vaithayapichet, S, Heller, RF. Patterns of antibiotic use in medical wards of a university hospital, Bangkok, Thailand. Rev Infect Dis 1990; 12:136141.Google Scholar
10.Thamlikitkul, V, Danchaivijitr, S, Kongpattanakul, S, Ckokloikaew, . Impact of an educational program on antibiotic use in a tertiary care hospital in developing country. J Clin Epidemiol 1998; 51:773778.CrossRefGoogle Scholar
11.Classen, DC, Burk, JP, Wenzel, RP. Infectious diseases consultation: impact on outcomes for hospitalized patients and results of a preliminary study. Clin Infect Dis 1997; 24:468470.Google Scholar
12.Byl, B, Clevenbergh, P, Jacobs, F, et al. Impact of infectious diseases specialists and microbiology data on the appropriateness of antimicrobial therapy for bacteremia. Clin Infect Dis 1999; 29:6066.CrossRefGoogle ScholarPubMed
13.Tice, AD. Editorial response: impact of infectious diseases specialists. Clin Infect Dis 1999; 29:6768.Google Scholar
14.Johnson, JR. Impact of infectious diseases specialists. Clin Infect Dis 2000; 30:838839.Google Scholar
15.Petrak, RM, Sexton, DJ, Butera, ML, et al. The value of an infectious diseases specialist. Clin Infect Dis 2003; 36:10131017.CrossRefGoogle ScholarPubMed