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Inactivation of replication-competent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on common surfaces by disinfectants

Part of: SARS-CoV-2/COVID-19

Published online by Cambridge University Press:  26 January 2022

Zachary C. Pope Open the ORCID record for Zachary C. Pope [Opens in a new window] ,
Carla M. Weisend ,
Aditya Shah ,
Hideki Ebihara  and
Stacey A. Rizza
Zachary C. Pope*
Affiliation:
Well Living Lab, Rochester, Minnesota Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota
Carla M. Weisend
Affiliation:
Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota
Aditya Shah
Affiliation:
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota
Hideki Ebihara
Affiliation:
Department of Virology 1, National Institute of Infectious Diseases, Tokyo, Japan
Stacey A. Rizza
Affiliation:
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota
*
Author for correspondence: Zachary C. Pope, E-mail: pope.zachary@mayo.edu or zachary.pope@delos.com
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Abstract

This experimental laboratory-based study evaluated two disinfectants’ efficacy against replication-competent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) on three surfaces. Disinfectants were effictive at eliminating the presence, viability, and subsequent replication of SARS-CoV-2 on all surfaces. Although SARS-CoV-2 likely spreads primarily via airborne transmission, layered mitigation should include high-touch surface disinfection.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 3 , March 2023 , pp. 504 - 506
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Copyright
© Delos Living LLC. and Mayo Clinic, 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

Greenhalgh, T, Jimenez, JL, Prather, KA, Tufekci, Z, Fisman, D, Schooley, R. Ten scientific reasons in support of airborne transmission of SARS-CoV-2. Lancet 2021. doi: 10.1016/S0140-6736(1021)00869-00862.CrossRefGoogle Scholar
Eilts, SM, Li, L, Pope, ZC, Hogan, CJ Jr Characterization of exhaled particle deposition and ventilation in an indoor setting. Atmos Environ 2021. doi: 10.1016/j.atmosenv.2021.118602.CrossRefGoogle Scholar
Lednicky, JA, Lauzardo, M, Fan, ZH, et al. Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients. Int J Infect Dis 2020;100:476–482.10.1016/j.ijid.2020.09.025CrossRefGoogle ScholarPubMed
National Institute for Occupational Safety and Health (NIOSH). Hierarchy of controls. Centers for Disease Control and Prevention website. https://www.cdc.gov/niosh/topics/hierarchy/default.html. Published 2015. Accessed June 14, 2020.Google Scholar
van Doremalen, N, Bushmaker, T, Morris, DH, et al. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med 2020;382:1564–1567.10.1056/NEJMc2004973CrossRefGoogle ScholarPubMed
Correa, MCM, Leal, FE, Boas, LSV, et al. Prolonged presence of replication-competent SARS-CoV-2 in midly symptomatic individuals: a report of two cases. J Med Virol 2021. doi: 10.1002/jmv.27021.CrossRefGoogle Scholar
Hierholzer, J, Killington, R. Virus isolation and quantitation. In: Mahy, B, Kangro, H, eds. Virology Methods Manual. San Diego, CA: Academic Press; 1996:25–46.10.1016/B978-012465330-6/50003-8CrossRefGoogle Scholar
Pope, ZC, Kottke, TJ, Shah, A, Vile, RG, Rizza, SA. Inactivation of replication-competent vesicular stomatitis virus as SARS-CoV-2 surrogate on common surfaces by disinfectants. Int J Environ Res Public Health 2021. doi: 10.3390/ijerph18147714.CrossRefGoogle Scholar
Xiling, G, Yin, C, Ling, W, et al. In vitro inactivation of SARS-CoV-2 by commonly used disinfection products and methods. Sci Rep 2021. doi: 0.1038/s41598-41021-82148-w.CrossRefGoogle Scholar
Meyers, C, Kass, R, Goldenberg, D, Milici, J, Alam, S, Robison, R. Ethanol and isopropanol inactivation of human coronavirus on hard surfaces. J Hosp Infect 2021;107:45–49.10.1016/j.jhin.2020.09.026CrossRefGoogle ScholarPubMed