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Human T-Cell Lymphotropic Virus-Type I

Published online by Cambridge University Press:  21 June 2016

Julie Larkin
Affiliation:
Division of Infectious and Tropical Diseases, Department of Internal Medicine, University of South Florida College of Medicine, ‘Tampa, Florida
John T. Sinnott IV*
Affiliation:
Department of Epidemiology, The Tampa General Hospital, ‘Tampa, Florida
Joshua Weiss
Affiliation:
Division of Infectious and Tropical Diseases, Department of Internal Medicine, University of South Florida College of Medicine, ‘Tampa, Florida
Douglas A. Holt
Affiliation:
Division of Infectious and Tropical Diseases, Department of Internal Medicine, University of South Florida College of Medicine, ‘Tampa, Florida
*
Director of Epidemiology, The Tampa General Hospital, PO Box 1289, Tampa, FL 33601

Extract

Human T-cell lymphotropic virus type-1 (HTLV-I) is a recently recognized retrovirus identified as the cause of adult T-cell leukemia-lymphoma (ATLL) and HTLV-I-associated myelopathy (TSPI HAM). HTLV-I, a member of the Retroviridae family of viruses, was first described in 1980 after the isolation of the virus from a patient with a T-cell lymphoma. These pathogenic retroviruses are typically divided into the Oncovirinae and Lentivirinae. The oncovirus group, including HTLV-I, HTLV-II and bovine leukemia virus (BLV), is generally associated with tumors. The lentiviruses are associated with immune deficiency and/or neurologic disease, and include agents such as the visna virus of sheep and the human immunodeficiency virus type-1 and -2 HIV-1 and HIV-2).

Type
Special Sections
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1990

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