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Effects of Chlorhexidine Oral Decontamination on Respiratory Colonization during Mechanical Ventilation in Intensive Care Unit Patients

Published online by Cambridge University Press:  02 January 2015

Douwe F. Postma ,
Sanjay U. C. Sankatsing ,
Steven F. T. Thijsen  and
Henrik Endeman
Douwe F. Postma*
Affiliation:
Department of Internal Medicine, Diakonessenhuis, Utrecht, the Netherlands
Sanjay U. C. Sankatsing
Affiliation:
Department of Internal Medicine, Diakonessenhuis, Utrecht, the Netherlands
Steven F. T. Thijsen
Affiliation:
Department of Medical Microbiology, Diakonessenhuis, Utrecht, the Netherlands
Henrik Endeman
Affiliation:
Department of Intensive Care Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands
*
University Medical Centre Utrecht, Julius Center for Health Sciences, PO Box 85500, 3508 GA, Utrecht, the Netherlands (d.f.postma@umcutrecht.nl)
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Abstract

We conducted a retrospective cohort study to assess respiratory colonization before and after the use of chlorhexidine oral decontamination among a cohort of intensive care unit patients who received mechanical ventilation. We observed a decrease in the prevalence of Enterobacteriaceae and an increase in the incidence of fungal colonization. Chlorhexidine oral decontamination might have a differential effect on respiratory colonization.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 33 , Issue 5 , May 2012 , pp. 527 - 530
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2012

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