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Effect on the reduction of bacterial load after surgical hand antisepsis with triclosan 0.5% compared to triclosan 0.5% followed by 70% alcoholic solution

Published online by Cambridge University Press:  22 December 2021

Luis Santé
Affiliation:
Servicio de Anestesiología y Reanimación, Hospital Clínico San Carlos, Universidad Complutense, Madrid, Spain
María Luisa Gómez-Lus
Affiliation:
Área de Microbiología, Departamento de Medicina, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain
Carlos Martin-Villa
Affiliation:
Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, Madrid, Spain
Ricardo Becerro-de-Bengoa-Vallejo
Affiliation:
Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, Madrid, Spain
Luis Alou*
Affiliation:
Área de Microbiología, Departamento de Medicina, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain
David Sevillano
Affiliation:
Área de Microbiología, Departamento de Medicina, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain
*
Author for correspondence: Luis Alou, E-mail: luisalou@ucm.es

Abstract

Triclosan 0.5% by scrubbing does not meet the UNE-EN12791 criteria to be used in the surgical hand preparation (SHP). Triclosan 0.5% by scrubbing followed by ethanol 70% hand rubbing is suitable without the additional characteristic of sustained effect. This limited effectiveness implies that triclosan should be avoided in SHP given the restrictions on its use in consumer antiseptic products. The trial was registered at ClinicalTrials.gov (ID: NCT04538365).

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

WHO guidelines on hand hygiene in health care. World Health Organization website. https://www.who.int/publications-detail-redirect/9789241597906. Published 2009. Accessed December 10, 2021.Google Scholar
Jones, RD, Jampani, HB, Newman, JL, Lee, AS. Triclosan: a review of effectiveness and safety in healthcare settings. Am J Infect Control 2000;28:184196.CrossRefGoogle Scholar
Nicolay, CR. Hand hygiene: an evidence-based review for surgeons. Int J Surg 2006;4:5365.CrossRefGoogle ScholarPubMed
Commission decision of 27 January 2016 not approving triclosan as an existing active substance for use in biocidal products for product type 1. J Eur Communities 2016;L21:8.Google Scholar
European Norm EN 12791. UNE EN 12791:2016+A1:2018 Chemical disinfectants and antiseptics—surgical hand disinfection—test method and requirements (phase 2, step 2). European Standards website. https://www.en-standard.eu/une-en-12791-2016-a1-2018-chemical-disinfectants-and-antiseptics-surgical-hand-disinfection-test-method-and-requirements-phase-2-step-2/. Published 2018. Accessed December 10, 2021.Google Scholar
De Bengoa Vallejo, RB, Fernandez, DS, Cervera, LA, et al. Effectiveness of surgical hand antisepsis using chlorhexidine digluconate and parachlorometaxylenol hand scrub crossover trial. Medicine (Baltimore) 2018;97:e12831.CrossRefGoogle Scholar
Giuliano, CA, Rybak, MJ. Efficacy of triclosan as an antimicrobial hand soap and its potential impact on antimicrobial resistance: a focused review. Pharmacotherapy 2015;35:328336.10.1002/phar.1553CrossRefGoogle ScholarPubMed
Kim, SA, Moon, H, Lee, K, Rhee, MS. Bactericidal effects of triclosan in soap both in vitro and in vivo. J Antimicrob Chemother 2015;70:33453352.Google ScholarPubMed
Martin-Villa, C, Becerro-De-Bengoa-Vallejo, R, Alou, L, et al. Comparing rubbing and scrubbing surgical hand antisepsis with propan-1-ol 60% in accordance with European regulation UNE-EN 12791:2016+A1:2018. Infect Control Hosp Epidemiol 2021;42:1382–1384.CrossRefGoogle Scholar
Rotter, M. Hand washing and hand disinfection. In: Mayhall, CG, ed. Hospital Epidemiology and Infection Control, second edition. Philadelphia: Lippincott Williams & Wilkins; 1999:13391355.Google Scholar