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Carbapenem De-escalation Therapy in a Resource-Limited Setting

Published online by Cambridge University Press:  02 January 2015

Anucha Apisarnthanarak ,
Nuntanij Bhooanusas ,
Apiwat Yaprasert  and
Linda M. Mundy
Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases, Thammasat University Hospital, Pratumthani, Thailand
Nuntanij Bhooanusas
Affiliation:
Division of Infectious Diseases, Thammasat University Hospital, Pratumthani, Thailand
Apiwat Yaprasert
Affiliation:
Padreaw Medical Equipment Shop, Chachoengsao, Thailand
Linda M. Mundy
Affiliation:
Bryn Mawr, Pennsylvania
*
Division of Infectious Diseases, Thammasat University Hospital, Pratumthani, Thailand, 12120 (anapisarn@yahoo.com)
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Abstract

Pulmonary infection (P = .01) and an infectious diseases consultation (P = .04) were associated with carbapenem de-escalation; pulmonary infection and septic shock were associated with unsuccessful de-escalation. Successful de-escalaltion was associated with lower mortality (0% vs 23%; P < .001) and shorter duration of carbapenem use (4 vs 10 days; P ≤.001).

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 34 , Issue 12 , December 2013 , pp. 1310 - 1313
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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