Hostname: page-component-8448b6f56d-jr42d Total loading time: 0 Render date: 2024-04-18T17:07:15.040Z Has data issue: false hasContentIssue false
  • English
  • Français

Association between Methicillin-Resistant Staphylococcus aureus Colonization and Infection May Not Differ by Age Group

Published online by Cambridge University Press:  02 January 2015

Adebola O. Ajao ,
Anthony D. Harris ,
J. Kristie Johnson ,
Mary-Claire Roghmann ,
Eli N. Perencevich ,
Marin L. Schweizer ,
Min Zhan ,
Wilbur H. Chen  and
Jon P. Furuno
Adebola O. Ajao
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Anthony D. Harris
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
J. Kristie Johnson
Affiliation:
Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland
Mary-Claire Roghmann
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
Eli N. Perencevich
Affiliation:
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa
Marin L. Schweizer
Affiliation:
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa
Min Zhan
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Wilbur H. Chen
Affiliation:
Veterans Affairs Maryland Health Care System, Baltimore, Maryland
Jon P. Furuno*
Affiliation:
Department of Pharmacy Practice, Oregon State University /Oregon Health and Science University College of Pharmacy, Portland, Oregon
*
OSU/OHSU College of Pharmacy, Department of Pharmacy Practice, 3303 SW Bond Avenue, CH12C, Portland, OR 97239 (furuno@ohsu.edu)
Get access Rights & Permissions [Opens in a new window]

Abstract

We assessed whether age modified the association between methicillin-resistant Staphylococcus aureus (MRSA) anterior nares colonization and subsequent infection. Among 7,405 patients (9,511 admissions), MRSA colonization was significantly associated with infection (adjusted odds ratio, 13.7 [95% confidence interval, 7.325.7]) but did not differ significantly by age group.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 34 , Issue 1 , January 2013 , pp. 93 - 95
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Cosgrove, SE, Sakoulas, G, Perencevich, EN, Schwaber, MJ, Karchmer, AW, Carmeli, Y. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis 2003;36:53–59.10.1086/345476Google Scholar
2. Mest, DR, Wong, DH, Shimoda, KJ, Mulligan, ME, Wilson, SE. Nasal colonization with methicillin-resistant Staphylococcus aureus on admission to the surgical intensive care unit increases the risk of infection. Anesth Analg 1994;78:644–650.10.1213/00000539-199404000-00005Google Scholar
3. Roghmann, MC, Siddiqui, A, Plaisance, K, Standiford, H. MRSA colonization and the risk of MRSA bacteraemia in hospitalized patients with chronic ulcers. J Hosp Infect 2001;47:98–103.10.1053/jhin.2000.0903Google Scholar
4. Harris, AD, Furuno, JP, Roghmann, MC, et al. Targeted surveillance of methicillin-resistant Staphylococcus aureus and its potential use to guide empiric antibiotic therapy. Antimicrob Agents Chemother 2010;54:3143–3148.10.1128/AAC.01590-09Google Scholar
5. Furuno, JP, McGregor, JC, Harris, AD, et al. Identifying groups at high risk for carriage of antibiotic-resistant bacteria. Arch Intern Med 2006;166:580–585.10.1001/archinte.166.5.580Google Scholar
6. Horan, TC, Andrus, M, Dudeck, MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309–332.10.1016/j.ajic.2008.03.002Google Scholar
7. Deyo, RA, Cherkin, DC, Ciol, MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol 1992;45:613–619.10.1016/0895-4356(92)90133-8Google Scholar
8. Pujol, M, Pena, C, Pallares, R, et al. Nosocomial Staphylococcus aureus bacteremia among nasal carriers of methicillin-resistant and methicillin-susceptible strains. Am J Med 1996;100:509–516.10.1016/S0002-9343(96)00014-9Google Scholar
9. Graffunder, EM, Venezia, RA. Risk factors associated with nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection including previous use of antimicrobials. J Antimicrob Chemother 2002;49:999–1005.10.1093/jac/dkf009Google Scholar