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Use of whole-genome sequencing to investigate a cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in emergency department personnel

Published online by Cambridge University Press:  04 May 2021

Ernest R. Chan
Affiliation:
Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio
Lucas D. Jones
Affiliation:
Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio
Sarah N. Redmond
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio
Maria E. Navas
Affiliation:
Pathology and Laboratory Medicine Service, Louis Stokes Cleveland Veterans’ Affairs (VA) Medical Center, Cleveland, Ohio
Nataliya M. Kachaluba
Affiliation:
Pathology and Laboratory Medicine Service, Louis Stokes Cleveland Veterans’ Affairs (VA) Medical Center, Cleveland, Ohio
Trina F. Zabarsky
Affiliation:
Infection Control Department, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Davinder Bhullar
Affiliation:
Personnel Health Department, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Jennifer L. Cadnum
Affiliation:
Research Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Peter A. Zimmerman
Affiliation:
The Center for Global Health & Diseases, Case Western Reserve University, Cleveland, Ohio
Curtis J. Donskey*
Affiliation:
Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
*
Author for correspondence: Curtis J. Donskey, E-mail: Curtis.Donskey@va.gov

Abstract

Several recent reports have raised concern that infected coworkers may be an important source of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) acquisition by healthcare personnel. In a suspected outbreak among emergency department personnel, sequencing of SARS-CoV-2 confirmed transmission among coworkers. The suspected 6-person outbreak included 2 distinct transmission clusters and 1 unrelated infection.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

a

Authors of equal contribution.

b

Study supervision authors of equal contribution.

References

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Use of whole-genome sequencing to investigate a cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in emergency department personnel
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