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Impact of antibiotic heterogeneity by periodic antibiotic monitoring and supervision strategy at two units with different prevalences of multidrug-resistant organisms

Published online by Cambridge University Press:  09 June 2021

Surachai Chaononghin
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Kittiya Jantarathaneewat
Affiliation:
Department of Pharmaceutical Care, Faculty of Pharmacy, Thammasat University, Prathum Thani, Thailand
David J. Weber
Affiliation:
University of North Carolina, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States
David K. Warren
Affiliation:
Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri, United States
Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
*
Author for correspondence: Anucha Apisarnthanarak, E-mail: anapisarn@yahoo.com

Abstract

In an intensive care unit, antibiotic heterogeneity led to an increase in antibiotic heterogeneity index (P = .002) and a reduction in carbapenem-resistance Enterobacteriaceae incidence (P = .04). In a general medicine unit with low prevalence of multidrug-resistant organisms, antibiotic heterogeneity index and incidence of multidrug-resistant organisms did not improve.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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