Hostname: page-component-cd9895bd7-q99xh Total loading time: 0 Render date: 2024-12-13T16:53:39.519Z Has data issue: false hasContentIssue false

The Emergence of Resistant Strains of Acinetobacter baumannii: Clinical and Infection Control Implications

Published online by Cambridge University Press:  02 January 2015

Marie Eve Dy
Affiliation:
Department of Medicine, St Vincent's Hospital and Medical Center, New York City, New York
Jill A. Nord*
Affiliation:
Department of Medicine, St Vincent's Hospital and Medical Center, New York City, New York
Vincent J. LaBombardi
Affiliation:
Department of Laboratories, St Vincent's Hospital and Medical Center, New York City, New York
Jay W. Kislak
Affiliation:
Department of Medicine, St Vincent's Hospital and Medical Center, New York City, New York
*
St Vincent's Hospital and Medical Center, 153 West 11th St, Cronin 1003, New York, NY 10011

Abstract

A prospective study was undertaken to determine colonization rates, susceptibility profiles, and outcomes in patients with clinical isolates of Acinetobacter baumannii. Fifty percent of patients became colonized with A baumannii, and 29% of these patients had clinical and colonizing isolates with discordant susceptibility profiles, without apparent relation to antibiotic use. Barrier infection control measures are necessary to prevent nosocomial transmission.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Bergogne-Berezin, E, Joly-Guillou, ML. Hospital infection with Acinetobacter spp: an increasing problem. J Hosp Infect 1991;18(suppl A):250255.Google Scholar
2.Contant, J, Kemeny, E, Oxley, C, Perry, E, Garber, G. Investigation of an outbreak of Acinetobacter calcoaceticus var anitratus infections in an adult intensive care unit. Am J Infect Control 1990;18:288291.Google Scholar
3.Go, ES, Urban, C, Burns, J, Kreiswirth, B, Eisner, W, Mariano, N, et al. Clinical and molecular epidemiology of Acinetobacter infections sensitive only to polymyxin B and sulbactam. Lancet 1994;344:13291332.Google Scholar
4.Cefai, C, Richards, J, Gould, FK, McPeake, P. An outbreak of Acinetobacter respiratory tract infection resulting from incomplete disinfection of ventilatory equipment. J Hosp Infect 1990;15:177182.CrossRefGoogle ScholarPubMed
5.Sherertz, RJ, Sullivan, ML. An outbreak of infections with Acinetobacter calcoaceticus in burn patients: contamination of patients' mattresses. J Infect Dis 1985;151:252258.CrossRefGoogle ScholarPubMed
6.Patterson, JE, Vecchio, J, Pantelick, EL, Farrel, P, Mazon, D, Zervos, MJ, et al. Association of contaminated gloves with transmission of Acinetobacter calcoaceticus var anitratus in an intensive care unit. Am J Med 1991;91:479483.CrossRefGoogle Scholar
7.Allen, KD, Green, HT. Hospital outbreak of multiresistant Acinetobacter anitratus: an airborne mode of spread? J Hosp Infect 1987;9:110119.Google Scholar
8.Timsit, JF, Garrait, V, Misset, B, Goldstein, FW, Renaud, B, Carlet, J. The digestive tract is a major site for Acinetobacter baumannii colonization in intensive care unit patients. J Infect Dis 1993;168:13361337.Google Scholar
9.Buxton, AE, Anderson, RL, Werdegar, D, Atlas, E. Nosocomial respiratory tract infection and colonization with Acinetobacter calcoaceticus: epidemiologic characteristics. Am J Med 1978;65:507513.Google Scholar
10.Corbella, X, Pujol, M, Ayats, J, Sendra, M, Ardanuy, C, Dominique, MAet al. Relevance of digestive tract colonization in the epidemiology of nosocomial infections due to multiresistant Acinetobacter baumannii. Clin Infect Dis 1996;23:329334.CrossRefGoogle ScholarPubMed