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Downstream Impact of Urine Cultures Ordered without Indication at Two Acute Care Teaching Hospitals

Published online by Cambridge University Press:  02 January 2015

Jerome A. Leis*
Affiliation:
Division of Infectious Diseases, Department of Medicine, University Health Network, Toronto, Ontario, Canada
Wayne L. Gold
Affiliation:
Division of Infectious Diseases, Department of Medicine, University Health Network, Toronto, Ontario, Canada
Nick Daneman
Affiliation:
Division of Infectious Diseases, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Kaveh Shojania
Affiliation:
Department of Medicine, Sunnybrook Health Sciences Centre, and, University of Toronto Centre for Patient Safety Toronto, Ontario, Canada
Allison McGeer
Affiliation:
Division of Infectious Diseases, Department of Medicine, University Health Network, Toronto, Ontario, Canada Department of Microbiology, University Health Network, /Mount Sinai Hospital, Toronto, Ontario, Canada
*
200 Elizabeth Street, 13EN-213, University Health Network, Toronto, Ontario M5G 2C4, Canada (jerome.leis@mail.utoronto.ca)

Extract

Antimicrobial therapy for asymptomatic bacteriuria (ASB) is recommended for pregnant patients and those undergoing genitourinary procedures. In other populations, treatment has not been demonstrated to confer benefit and is associated with adverse drug reactions, selection for infection with increasingly drug-resistant bacteria, and Clostridium difficile infection. We undertook a prospective audit of urine culture ordering practices among medical and surgical inpatients at 2 acute care teaching hospitals to identify the proportion of urine cultures ordered without clinical indication that lead to antimicrobial therapy for ASB.

During August and September 2012, consecutive urine cultures from nonpregnant ward patients were identified within 24 hours of culture ordering. Each patient was interviewed by the study team to determine the presence of urinary tract infection (UTI) using standard surveillance criteria. Non-catheterized patients met clinical indications for UTI if they had fever (temperature >38°C) without another explanation or at least 1 urinary symptom (dysuria, urgency, frequency, costovertebral angle tenderness, or suprapubic pain or tenderness). Catheterized patients met clinical indications for UTI if they had fever, suprapubic pain, or costovertebral angle tenderness. Other reasons for ordering cultures were documented on the basis of care provider interviews before culture results were known. Culture results and antimicrobial prescriptions were documented 72 hours later. The study was approved by the research ethics boards of Mount Sinai Hospital (472 beds) and University Health Network (408 beds; Toronto General Hospital site).

Type
Research Briefs
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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References

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