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Hst-3: an X-linked hybrid sterility gene

Published online by Cambridge University Press:  14 April 2009

Jean-Louis Guénet ,
Claude Nagamine ,
Dominique Simon-Chazottes ,
Xavier Montagutelli  and
François Bonhomme
Jean-Louis Guénet*
Affiliation:
Unité de Génétique des Mammifères de l'Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.
Claude Nagamine
Affiliation:
Howard Hughes Medical Institute, University of California, Parnassus and Third Avenues, U-426 San Francisco, CA 94143, USA.
Dominique Simon-Chazottes
Affiliation:
Unité de Génétique des Mammifères de l'Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.
Xavier Montagutelli
Affiliation:
Unité de Génétique des Mammifères de l'Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.
François Bonhomme
Affiliation:
Institut des Sciences de l'Evolution UA au CNRS 327 Place Eugène Bataillon, 34060 Montpellier Cedex, France
*
* Corresponding author.

Summary

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A gene, Hst-3, responsible for sterility in F1 males from crosses between Mus spretus and laboratory strains of mice such as C57BL/6, has been localized on the distal part of the X chromosome, using both DNA probes and biochemical markers on a panel of Fl(C57BL/6 × SEG) × C57BL/6 backcross males. This gene may be a model for studying mammalian hybrid sterility.

Type
Research Article
Information
Genetics Research , Volume 56 , Issue 2-3 , October 1990 , pp. 163 - 165
Copyright
Copyright © Cambridge University Press 1990

References

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