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Genetic control of DNA specificity in Pseudomonas aeruginosa
Published online by Cambridge University Press: 14 April 2009
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Genotypic and phenotypic changes of HCM in P. aeruginosa are due to a variety of causes. In addition to interstrain genetic differences and the semi-permanent effects of growth at 43°C, mutations affecting both restriction and modification have been isolated by direct selection and through the pleiotropic effects of p–fluorophenylalanine resistance mutations. It is suggested that some of these changes affecting HCM may be taking place through alterations of the ribosomes.
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