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Effect of Y chromosome and H-2 complex derived from Japanese wild mouse on sperm morphology

Published online by Cambridge University Press:  14 April 2009

Dong-Sang Suh ,
Jozefa Styrna  and
Kazuo Moriwaki
Dong-Sang Suh
Affiliation:
Genetic Engineering Center, Korea Advanced Institute of Science and Technology, P.O. Box 131, Cheongryang, Seoul, Korea.
Jozefa Styrna
Affiliation:
Department of Genetics and Evolution, Institute of Zoology, Jagiellonian University, Karasia 6, 30-060 Krakow, Poland
Kazuo Moriwaki
Affiliation:
Department of Cell Genetics, National Institute of Genetics, Yata-1111, Mishima, Shizuoka-ken 411, Japan
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Segregation of sperm abnormality level and H-2 haplotypes was investigated in F2 hybrid males obtained from reciprocal crosses involving two B10.congenic strains carrying H-2 and the Y chromosome of Japanese wild mice: B10.MOL-OHM (H-2ωm4, 23·1% of sperm abnormalities) and B10.MOL-OKB (H-2ωm8, 11·1% of sperm abnormalities). In both types of crosses mean levels of abnormal spermatozoa were significantly higher for males typed as H-2ωm4/H-2ωm4 than for heterozygous H-2ωm4/H-2ωm8 or homozygous H-2ωm8/H-2ωm8. These results suggest that the gene for high sperm abnormality is linked to H-2 complex of the B10.MOL-OHM strain.

Type
Research Article
Information
Genetics Research , Volume 53 , Issue 1 , February 1989 , pp. 17 - 19
Copyright
Copyright © Cambridge University Press 1989

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