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Diagnosis of fragile X syndrome

Published online by Cambridge University Press:  10 October 2008

JC Mulley  and
GR Sutherland
JC Mulley*
Affiliation:
Centre for Medical Genetics, Women’s and Children’s Hospital, North Adelaide, Australia
GR Sutherland
Affiliation:
Centre for Medical Genetics, Women’s and Children’s Hospital, North Adelaide, Australia
*
Dr JC Mulley, Department of Cytogenetics and Molecular Genetics, Women’s and Children’s Hospital, 72 King William Road, North Adelaide SA 5006, Australia.
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Extract

Fragile X syndrome accounts for between one third and one half of all X-linked mental retardation. It is the most common cause of familial intellectual handicap and is second in prevalence only to Down’s syndrome among the mental retardations. The syndrome is known to affect about 1 in 2500 males and a similar number of females. It has been detected in all ethnic groups with access to modern medicine. The economic and social costs of this disorder made the determination of its molecular basis a high priority.

Type
Articles
Information
Fetal and Maternal Medicine Review , Volume 6 , Issue 1 , February 1994 , pp. 1 - 15
Copyright
Copyright © Cambridge University Press 1994

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