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NON-ADRENERGIC, NON-CHOLINERGIC REFLEX SECRETION OF PAROTID SALIVA IN RATS ELICITED BY MASTICATION AND ACID APPLIED ON THE TONGUE

Published online by Cambridge University Press:  03 January 2001

J. Ekström
J. Ekström
Affiliation:
Department of Pharmacology, Institute of Physiology and Pharmacology, Göteborg University, Box 431, SE 405 30 Göteborg, Sweden
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Abstract

Chewing and acid on the tongue evoked a flow of saliva from the duct-cannulated parotid gland of the conscious rat despite pretreatment with atropine and adrenoceptor antagonists. This non-adrenergic, non-cholinergic (NANC) response depended on an intact parasympathetic innervation and was abolished by a tachykinin antagonist. The present findings are consistent with a physiological role for the secretory NANC mechanisms of the salivary glands.

Type
Rapid Communication
Information
Experimental Physiology , Volume 83 , Issue 5 , September 1998 , pp. 697 - 700
Copyright
© The Physiological Society 1998

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