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Substance Use During Pregnancy, Postpartum Depression and Child Outcomes: A Longitudinal Study

Published online by Cambridge University Press:  16 April 2020

M. Imaz
Affiliation:
Servei de Psiquiatria, Programa Psiquiatría Perinatal i de Recerca de Génere, Institut Clinic de Neurociéncies, Hospital Clinic, Seu Maternitat, Barcelona, Spain
E. Gelabert
Affiliation:
Hospital Clinic-IDIBAPS, IMIM-Hospital del Mar, Barcelona, Spain
P. Navarro
Affiliation:
Hospital Clinic-IDIBAPS, Barcelona, Spain
J. Sanjuan
Affiliation:
Hospital Clinico-Universidad de Valencia, Valencia, Spain
R. Guillamat
Affiliation:
Corporació Sanitaria Parc Taulí, Hospital Terrasa, Terrasa, Spain
A. Gutierrez
Affiliation:
Hospital Psiquiátrico, Instituto Pere Mata, Reus, Spain
I. Gorneman
Affiliation:
Fundación IMABIS, Hospital Carlos Haya, Málaga, Spain
F. Canellas
Affiliation:
Hospital Son Dureta, Palma de Mallorca, Spain
M. Gratacós
Affiliation:
Centre de Regulació Genómica, Barcelona, Spain
X. Costa
Affiliation:
SERGAS, Hospital Clínico Univesitario, Santiago de Compostela, Spain
M. Torrens
Affiliation:
IMIM - Hospital del Mar, Barcelona, Spain
L. García-Esteve
Affiliation:
Hospital Clinic-IDIBAPS, Barcelona, Spain
R. Martín-Santos
Affiliation:
Hospital Clinic-IDIBAPS, IMIM-Hospital del Mar, Barcelona, Spain

Abstract

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Introduction:

Although it is well know that the substance use during pregnancy has a negative impact on mother and child health, there are few data on pregnancy - related substance use as a risk factor for postpartum depression and child outcomes.

Aims: To determine maternal and child outcomes at 8 and 32 weeks postpartum of women who reported substance use during pregnancy.

Method:

This is a cohort study of 1804 Caucasian women in postpartum. Exclusion criteria: psychiatric disorders during pregnancy. Women were evaluated at 2-3 days, 8 and 32 weeks postpartum. Socio-demographic, obstetric, personal and family psychiatric history and substance use during pregnancy; the Edimburgh Postpartum Depression Scale (EPDS) were assessed. All women with EPDS>9 at 8 and 32 weeks were evaluated by a structured interview (DIGS) for DSM-III major depression.

Results:

The mean (SD) age was 31.7 (4.6). Forty-six percent of them were primiparous. Thirty-one percent has a family and 16% a psychiatry history. Fifty percent of women reported substance use during pregnancy: 42% caffeine, 21.6% nicotine, 8% alcohol and 0.6% cannabis. Incidence of major postpartum depression was: 12.7%. Incidence of: Apgar scores < 7 at 5 min after birth:0.4%, gestational age at delivery < 37 weeks:7.3%, birth weigt < 2.5 Kg:7.3%, and congenital malformations:1.4%.

Conclusions:

In the presentation, the maternal and child perinatal outcomes of women exposed to licit and ilicit drugs will be summarize and will include a discussion of the future clinical and research implications. This work has been done in part with Grants: GO3/184;FIS:PI04178;PI041635,PI041783,PI041779,PI041758,PI041761,PI041791,PI041766,PI041782,RD06/0001/1009; CIBER-SAM.

Type
S46-03
Copyright
Copyright © European Psychiatric Association 2009
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