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Sexual side effects in patients treated with desvenlafaxine: Anobservational study in daily practice

Published online by Cambridge University Press:  23 March 2020

B. Navarro ,
L. Perez ,
L. Erkoreka ,
A. Arroita  and
I. Perez
B. Navarro*
Affiliation:
Red de Salud Mental de Bizkaia, CSM Barakaldo, Bilbao, Spain
L. Perez
Affiliation:
Red de Salud Mental de Bizkaia, CSM Barakaldo, Bilbao, Spain
L. Erkoreka
Affiliation:
Red de Salud Mental de Bizkaia, CSM Barakaldo, Bilbao, Spain
A. Arroita
Affiliation:
Re de Salud Mental de Bizkaia, CSM Barakaldo, Bilbao, Spain
I. Perez
Affiliation:
Hospital Universitario Cruces, psiquiatría, Barakaldo, Spain
*
*Corresponding author.

Abstract

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Introduction

Sexual function is important for patients’ well-being but it is acommon side effect of SSRI and SNRI, included desvenlafaxine.

Objectives and aims

Evaluate incidence and characteristics of sexual dysfunction caused bydesvenlafaxine in the clinical practice.

Methods

One hundred and thirty-three patients with recently introduced desvenlafaxinetreatment are recruited from Barakldo and Uribe-Kosta Mental Health Centresin Biscay, Spain. UKU scale is administered to measure sexual side effects.Statistical analysis is performed using SPSS v.22.

Results

Sexual dysfunction is observed in 5 patients (3.7%) at 50 and 100 mg/d (2 and3 patients, respectively) desvenlafaxine doses. Two patients (1.5%) haveexperimented more than one sexual side effect. Regarding gender differences,the most frequent sexual dysfunctions are diminished sexual desire (5.5%)and erectile dysfunction (5.5%) in men and orgasmic dysfunction (1.2%) inwomen (P-values are 0.034; 0.034 and 0.408, respectively).Discontinuation is decided in 60% of patients.

Conclusions

Desvenlafaxine has a well-tolerated sexual side effect profile in generalpopulation. There are some gender-related differences both in presentationand perception, as it has been described with other drugs, and this shouldbe taken into account by prescriptors.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
EW444
Information
European Psychiatry , Volume 33 , Issue S1: Abstracts of the 24th European Congress of Psychiatry , March 2016 , pp. s227 - s228
Copyright
Copyright © European Psychiatric Association 2014
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