Skip to main content Accessibility help
×
Home
Hostname: page-component-544b6db54f-dkqnh Total loading time: 0.149 Render date: 2021-10-22T08:10:35.203Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Article contents

The mediating role of impulsivity in the relationship between suicidal behaviour and early traumatic experiences in depressed subjects

Published online by Cambridge University Press:  13 August 2021

F. Dal Santo*
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
J.J. Carballo
Affiliation:
Department Of Psychiatry, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Á. Velasco
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
L. Jiménez-Treviño
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
J. Rodríguez-Revuelta
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
C. Martínez-Cao
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
I. Irene Caro-Cañizares
Affiliation:
Department Of Psychiatry, Fundación Jiménez Díaz Hospital, Madrid, Spain
L. De La Fuente-Tomás
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
I. Menéndez-Miranda
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
L. González-Blanco
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
M.P. García-Portilla
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
J. Bobes
Affiliation:
Psychiatry, University of Oviedo, Oviedo, Spain
P.A. Saiz
Affiliation:
Department Of Psychiatry, University of Oviedo, Oviedo, Spain
*
*Corresponding author.

Abstract

HTML view is not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

Depressed patients with early traumatic experiences may represent a clinically distinct subtype with worse clinical outcome. Since early traumatic experiences alter the development of systems that regulate the stress response, certain personality features may influence coping strategies, putting individuals with depression and a history of early traumatic experiences at greater risk of suicidal behaviour.

Objectives

To determine whether impulsivity mediates the relationship between early traumatic experiences and suicidal behaviour in patients with major depressive disorder (MDD).

Methods

The sample included 190 patients [mean age (SD)=53.71 (10.37); females: 66.3%], with current MDD. The Childhood Trauma Questionnaire-Short Form (CTQ-SF), the List of Threatening Experiences (LTE), and the Barratt Impulsiveness Scale-11 (BIS-11) were used to assess childhood and adulthood adverse life events and impulsivity. We developed mediation models by bootstrap sampling methods.

Results

81 (42.6%) patients had previous suicide attempts (SA). CTQ-SF-Total and BIS-11-Total scores were higher in MDD patients with previous SA. Correlation analyses revealed significant correlations between the CTQ-SF-Total and BIS-11-Total, CTQ-SF-Total and HDRS-Total, and BIS-11-Total and HDRS-Total scores. Regression models found that CTQ-SF-Total, BIS-11-Total, and HDRS-Total scores were associated with SA. Mediation analyses further revealed the association between CTQ-SF-Total and SA was mediated by the indirect effect of the BIS-11-Total score (b=0.007, 95% CI=0.001, 0.015), after controlling for sex, HDRS-Total, and LTE-Total.

Conclusions

Impulsivity could mediate the influence of childhood trauma on suicidal behaviour. This will help understand the role of risk factors in suicidal behaviour and aid in the development of prevention interventions focused on modifiable mediators when risk factors are non-modifiable.

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
Submit a response

Comments

No Comments have been published for this article.
You have Access
Open access

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

The mediating role of impulsivity in the relationship between suicidal behaviour and early traumatic experiences in depressed subjects
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

The mediating role of impulsivity in the relationship between suicidal behaviour and early traumatic experiences in depressed subjects
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

The mediating role of impulsivity in the relationship between suicidal behaviour and early traumatic experiences in depressed subjects
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *