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Hemispheric function in disorganized type schizophrenia: performance on the Quality Extinction Test

Published online by Cambridge University Press:  16 April 2020

B Spivak ,
D Elimelech ,
R Ocring ,
R Mester ,
M Kotler  and
A Weizman
B Spivak
Affiliation:
Research Unit, Ness Ziona Health Center, Ness Ziona, Israel Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
D Elimelech
Affiliation:
Research Unit, Ness Ziona Health Center, Ness Ziona, Israel
R Ocring
Affiliation:
Research Unit, Geha Psychiatric Hospital and Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Petah Tikva, Israel
R Mester
Affiliation:
Research Unit, Ness Ziona Health Center, Ness Ziona, Israel Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
M Kotler
Affiliation:
Faculty of Medicine, Ben-Gurion University, Beer-Sheva, Israel
A Weizman*
Affiliation:
Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel Research Unit, Geha Psychiatric Hospital and Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Petah Tikva, Israel
*
*Correspondence and reprints: B. Spivak, M.D., Ness Ziona Mental Health Center, P.O.B. 1, Ness Ziona 74100, Israel
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Extract

We assessed hemisphere function in right-handed male chronic, disorganized type schizophrenic patients (N = 60, age range 18–45 years) using the Quality Extinction Test (QET), in comparison to 20 right-handed male healthy controls in the same age range. The QET analysis discriminated between the disorganized schizophrenic patients and the controls. QET results indicated that chronic schizophrenic patients were less sensitive to tactile stimuli in both hands as compared to controls. Furthermore, the sensitivity to tactile stimuli of the left hand was less than that of the right hand in the schizophrenic patients. In contrast, in the normal controls the sensitivity was similar in both hands. These results indicate possible right hemisphere dysfunction together with disturbance in interhemispheric transmission through the corpus callosum in chronic, disorganized type schizophrenic patients.

Keywords

chronic schizophreniacorpus callosumhemispheresQuality Extinction Test
Type
Original article
Information
European Psychiatry , Volume 15 , Issue 7 , November 2000 , pp. 402 - 406
Copyright
Copyright © 2001 Éditions scientifiques et médicales Elsevier SAS. All rights reserved

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