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Childhood psychopathological antecedents in early onset schizophrenia

Published online by Cambridge University Press:  16 April 2020

F. Muratori*
Affiliation:
University of Pisa, Pisa, Italy
F. Salvadori
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
G. D’Arcangelo
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
V. Viglione
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
L Picchi
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
*
*Corresponding author. Present address: c/o IRCCS Stella Maris, Via dei Giacinti, 2, 56018 Calambrone, Pisa, Italy. Tel.: +39 050 886 292; fax: +39 050 886 247. E-mail address: f.muratori@inpe.unipi.it (F. Muratori).
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Abstract

Objective

To describe the premorbid state of early onset schizophrenia (EOS).

Methods

Twenty-three adolescents with EOS were compared to a healthy control group (CG) and to a group of anorexic patients (AG). The premorbid state was studied through the CBCL and the data obtained were analyzed using ANOVA’s and t-test.

Results

During the premorbid period EOS showed significantly higher scores on all scales, relative to the CG, and only on some scales (social, thought and attention problems, and school competencies) relative to the AG.

Conclusions

Children who develop first episode psychosis during adolescence differ from children with normal development. The premorbid internalizing state is common to AG but social competencies and school problems are the most affected areas in EOS when compared to the AG. It is hypothesized that both EOS and AG can be considered as the expression of a previous vulnerability.

Type
Original article
Copyright
Copyright © Elsevier SAS 2005

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