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Assessment of cognitive function following a course of electroconvulsive therapy

Published online by Cambridge University Press:  13 August 2021

S. Ali ,
S. Kamel ,
J. Easow ,
R. Blasubramanian  and
P. Parvathy
S. Ali*
Affiliation:
Basildon Mental Health Unit Inpatients Grangewaters Ward, Essex partnership nhs trust, Basildon, United Kingdom
S. Kamel
Affiliation:
Basildon Mental Health Unit Inpatients Grangewaters Ward, Essex partnership nhs trust, Basildon, United Kingdom
J. Easow
Affiliation:
Basildon Mental Health Unit Inpatients Grangewaters Ward, Essex partnership nhs trust, Basildon, United Kingdom
R. Blasubramanian
Affiliation:
Basildon Mental Health Unit Inpatients Grangewaters Ward, Essex partnership nhs trust, Basildon, United Kingdom
P. Parvathy
Affiliation:
Basildon Mental Health Unit Inpatients Grangewaters Ward, Essex partnership nhs trust, Basildon, United Kingdom
*
*Corresponding author.

Abstract

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Introduction

ECT is a potentially life-saving treatment for patients with severe or treatment resistant depression. Cognitive function disturbances following ECT are generally transient, but could be of longer duration in some cases

Objectives

To assess the cognitive side effects in patients with affective disorders treated with a course of electroconvulsive therapy (ECT).

Methods

Cognitive functions of patients who undergo ECT was assessed prior to start of treatment, midway of the course of treatment and after end of the course of treatment using Montreal Cognitive Assessment (MoCA). We did a retrospective analysis of MoCA scores of 15 patients who received bilateral ECT in 2017-2018. In order to assess the efficacy of ECT in the treatment of their illness, we did a retrospective analysis of Montgomery Asberg Depression Rating Scale (MADRS) scores of 18 patients who received bilateral ECT in 2017-2018

Results

Only 7% of the patients who underwent ECT in our sample did have significant cognitive decline as per their MoCA scores. 28% of patients achieved complete remission in their depressive symptomes. 22% of patients continued on maintenance treatment. 95% of patients showed significant improvement in their symptoms following treatment with ECT where there symptoms reduced to either mild or minimal depressive symptoms.

Conclusions

Cognitive side effect was not a significant side effect in our sample of patients. We did see an improvement in cognitive function in a significant number of the sample of patients as they progressed with treatment, which coincided with improvement in their affective symptoms.

Keywords

ECTMOCAMADRSCognitive functions
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S488 - S489
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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