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An objective method for edge detection in MRI morphometry

Published online by Cambridge University Press:  16 April 2020

MS Keshavan
Affiliation:
Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O’Hara Street, Pittsburgh, PA15213
C Beckwith
Affiliation:
Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O’Hara Street, Pittsburgh, PA15213
W Bagwell
Affiliation:
Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O’Hara Street, Pittsburgh, PA15213
W Pettegrew
Affiliation:
Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O’Hara Street, Pittsburgh, PA15213
K Ranga Krishnan
Affiliation:
Department of Psychiatry, Duke University Medical Center, PO Box 3215, Durham, NC27710, USA
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Summary

We describe a simple method to objectively identify the threshold for edge detection in morphometric measurement of brain structures. This method correlates highly with the subjective operator-driven approach to edge detection. While the objective approach, using a histogram of pixel intensities, reduces rater bias and may reliably identify brain-CSF boundaries, its value in morphometric measurements of smaller cerebral structures may be somewhat limited.

Type
Short communication
Copyright
Copyright © European Psychiatric Association 1994

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