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Antipsychotic Medication Adherence Scale (AMAS): Development and preliminary psychometric properties

Published online by Cambridge University Press:  23 March 2020

M.J. Martins
Affiliation:
University of Coimbra, CINEICC, faculty of psychology and educational sciences, Coimbra, Portugal University of Coimbra, department of psychological medicine, Coimbra, Portugal
A.T. Pereira
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
C.B. Carvalho
Affiliation:
University of Coimbra, CINEICC, faculty of psychology and educational sciences, Coimbra, Portugal University of Azores, education department, Azores, Portugal
P. Castilho
Affiliation:
University of Coimbra, faculty of psychology and educational sciences, Coimbra, Portugal
A.C. Lopes
Affiliation:
Baixo Vouga hospital centre, department of psychiatry and mental health, Aveiro, Portugal
A. Oliveira
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
C. Roque
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
D. Mota
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
F. Tróia
Affiliation:
Baixo Vouga hospital centre, department of psychiatry and mental health, Aveiro, Portugal
M. Bajouco
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
N. Madeira
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
O. Matos
Affiliation:
Baixo Vouga hospital centre, department of psychiatry and mental health, Aveiro, Portugal
P. Santos
Affiliation:
Baixo Vouga hospital centre, department of psychiatry and mental health, Aveiro, Portugal
R. Leite
Affiliation:
Baixo Vouga hospital centre, department of psychiatry and mental health, Aveiro, Portugal
S. Morais
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
T. Santos
Affiliation:
Baixo Vouga hospital centre, department of psychiatry and mental health, Aveiro, Portugal
T. Santos
Affiliation:
Baixo Vouga hospital centre, department of psychiatry and mental health, Aveiro, Portugal
V. Nogueira
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
V. Santos
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
A. Macedo
Affiliation:
University of Coimbra, department of psychological medicine, Coimbra, Portugal
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Abstract

Introduction

Although being highly consensual that antipsychotic adherence is an important outcome predictor in psychosis, existing reviews have found mean rates of adherence around 40–60%. Several aspects, such as patient-related, medication-related, environmental-related variables have been described as important predictors.

Aims

This study aim is to develop, administer and present preliminary psychometric properties of a new scale for antipsychotic medication adherence that includes different types of predictors (clinical, psychosocial, and practical among others).

Methods

The “AMAS” was developed by a multidisciplinary team and was based on recent research on factors influencing antipsychotic adherence. The scale evolved from multiple drafts and experts were contacted in order to improve the final version. Over 50 patients with a diagnosis of a psychotic-spectrum disorder taking antipsychotic medication will be assessed with the “AMAS” and the Medication Adherence Rating Scale. Additionally, each patient's psychiatrist will fill in a form with demographic and clinical variables (such as type of symptoms, previous adherence problems, current adherence, insight and other relevant variables).

Results

This is an ongoing study and the sample is still being collected (scheduled finish date: February/2016). Our statistical analysis’ plan includes: reliability analysis (Chronbach's alpha, alpha if item deleted, inter item correlations and covariances and item-total correlations); validity (convergent validity); factorial analysis.

Conclusions

It is hypothesized that the “AMAS” will be a practical, reliable and valid unidimentional instrument with clinical utility assessing adherence to antipsychotics. The “AMAS” can be also useful in assessing intervention targets (e.g. psychoterapeutical, psychoeducational) to enhance adherence.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
EW540
Copyright
Copyright © European Psychiatric Association 2014

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