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1961 – HCV As a Traumatic Experience, Ptsd And Quality Of Life

Published online by Cambridge University Press:  15 April 2020

M. Morais-de-Jesus
Affiliation:
Postgraduate Program in Medicine and Health Sciences, Faculty of Medicine of Bahia, Federal University of Bahia
C.I. Rocha-Leite
Affiliation:
Postgraduate Program in Medicine and Health Sciences, Faculty of Medicine of Bahia, Federal University of Bahia
K.M. Pettersen
Affiliation:
Postgraduate Program in Medicine and Health Sciences, Faculty of Medicine of Bahia, Federal University of Bahia
R. Daltro-de-Oliveira
Affiliation:
Faculty of Medicine of Bahia, Federal University of Bahia, Salvador
A.D.D. Dias
Affiliation:
Postgraduate Program in Medicine and Health Sciences, Faculty of Medicine of Bahia, Federal University of Bahia
L.D.-D. Amaral
Affiliation:
Pontifícia Catholic University of São Paulo, São Paulo
P. Cavalcanti-Ribeiro
Affiliation:
University Hospital, Psychiatry Service and Department of Neurosciences and Mental Health, Faculty of Medicine of Bahia, Federal University of Bahia, Salvador
C.T. Santos
Affiliation:
Department of Exact Sciences, State University of Feira de Santana, Feira de Santana, Brazil
R. Borges-de-Oliveira
Affiliation:
Postgraduate Program in Medicine and Health Sciences, Faculty of Medicine of Bahia, Federal University of Bahia
L.C. Quarantini
Affiliation:
University Hospital, Psychiatry Service and Department of Neurosciences and Mental Health, Faculty of Medicine of Bahia, Federal University of Bahia, Salvador
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Abstract

Introduction

The HCV has been associated with significant impairment of quality of life, irrespective of the degree of liver injury. The association of this disease with psychiatric comorbidities, especially depression, has been well described in the scientific literature. However, despite also significantly affect the quality of life of individuals, the Posttraumatic Stress Disorder (PTSD) has not been well studied in this population.

Objective/aim

Evaluate whether individuals perceive the liver disease as a potentially traumatic experience and investigate the impact of PTSD diagnosis on health-related quality of life in hepatitis C virus-infected subjects.

Methods

We conducted a cross-sectional survey of 127 consecutive hepatitis C-infected outpatients. We investigated Traumatic Experiences and the subject's perception about the disease using the Trauma History Questionnaire. PTSD and others psychiatry diagnoses were assessed trough M.I.N.I. PLUS. Quality of life was assessed by the Short-Form 36.

Results

Approximately 38.6% of the patients perceived the hepatitis C as a traumatic experience, 60.7% had PTSD diagnosis. It were no associate with the disease severity (been eligible for transplant), however there was a significant association with diagnosis of PTSD (p = 0.003). Roughly 22% of the sample showed PTSD diagnosis. PTSD imposed a significant impairment in quality of life of individuals in seven of the eight domains in the bivariate and multivariate analysis. This difference remained significant after adjustment for covariates such as major depressive disorder comorbidity.

Conclusion

The results suggest high prevalence of PTSD diagnosis in VHC infected patients and it impose impairment in their quality of life.

Type
Other
Copyright
Copyright © European Psychiatric Association 2013

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