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1606 – Temperament In Individuals With Psychotic Disorders Before And After The Onset Of Illness

Published online by Cambridge University Press:  15 April 2020

J. Miettunen
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland Department of Psychiatry, Oulu University Hospital, Oulu, Finland Institute of Health Sciences, University of Oulu, Oulu, Finland
P. Juola
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland
E. Roivainen
Affiliation:
Cognitive Neuropsychology Laboratory, Verve Research, Oulu, Finland
J. Veijola
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland Department of Psychiatry, Oulu University Hospital, Oulu, Finland
A. Alaräisänen
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland
M. Isohanni
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland Department of Psychiatry, Oulu University Hospital, Oulu, Finland
E. Jääskeläinen
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland Department of Psychiatry, Oulu University Hospital, Oulu, Finland
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Abstract

Introduction

The Temperament and Character Inventory (TCI) is used to measure novelty seeking (NS), harm avoidance (HA), reward dependence RD), and persistence (P).

Objectives

We will study temperament in individuals with psychosis and healthy controls.

Aim

We aim to study the stability of temperament in individuals with psychotic disorders (with onset of illness before and after first follow-up) and in healthy controls.

Methods

As part of the 31-year follow-up survey of the prospective population based Northern Finland 1966 Birth Cohort, the TCI was filled by a large sample of individuals. A subsample of psychotic individuals, with the onset of illness before (n=16) or after (n=15) the 31-year follow-up, and healthy controls (n=117) filled in these scales again at the age of 43. We studied also the association between psychotic symptoms and premorbid temperament.

Results

The 31-year and 43-year temperament scores correlated strongly among controls (Pearson's r: NS 0.68, HA 0.60, RD 0.56, P 0.54), whereas correlations among psychotic individuals with the onset of psychosis before first follow-up were weaker (NS 0.38, HA 0.50, RD 0.17, P 0.53). High HA before the onset of illness (at age of 31 years) associated significantly with a lower likelihood of remission and with more negative, disorganization and total symptoms in the PANSS. High NS before illness associated with a higher likelihood of remission according to the PANSS.

Conclusions

Temperament was stable among controls, and more unstable in individuals with psychoses. Premorbid harm avoidance and novelty seeking predicts the clinical outcome in schizophrenia.

Type
Research Article
Copyright
Copyright © European Psychiatric Association 2013

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