Hostname: page-component-8448b6f56d-42gr6 Total loading time: 0 Render date: 2024-04-20T01:12:47.326Z Has data issue: false hasContentIssue false

The 2-year stability of neurological soft signs after a first episode of non-affective psychosis

Published online by Cambridge University Press:  16 April 2020

Marco P.M. Boks*
Affiliation:
Department of Psychiatry, University Hospital Groningen, PO box 30.001, 9700 RBGroningen, The Netherlands Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, B01.206, PO box 85500, 3508 GAUtrecht, The Netherlands
Jean-Paul Selten
Affiliation:
Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, B01.206, PO box 85500, 3508 GAUtrecht, The Netherlands
Stuart Leask
Affiliation:
Division of Psychiatry, University of Nottingham, Duncan Macmillan House, Porchester Road, NottinghamNG3 6AA, UK
Robert J. Van den Bosch
Affiliation:
Department of Psychiatry, University Hospital Groningen, PO box 30.001, 9700 RBGroningen, The Netherlands
*
*Corresponding author. E-mail address: m.p.m.boks@psych.azu.nl (M.P.M. Boks), j.p.selten@azu.nl (J.-P. Selten), stuart.leask@nottingham.ac.uk (S. Leask), r.j.van.den.bosch@med.rug.nl (R.J.Van den Bosch).
Get access

Abstract

We examined the 2-year stability of neurological soft signs (NSS) in 29 patients after a first episode of psychosis. The numbers of NSS at inclusion and at 2 years follow-up were similar, but there was a significant increase in the numbers of NSS in the sub-group of patients whose dosage of antipsychotic medication had increased over time.

Type
Original articles
Copyright
Copyright © Elsevier SAS 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Boks, M.P., Liddle, P.F., Burgerhof, J.G., Knegtering, R., van den Bosch, R.J.Neurological soft signs discriminating mood disorders from first episode schizophrenia. Acta Psychiatr. Scand 2004;110(1):2935.CrossRefGoogle ScholarPubMed
Boks, M.P.M., Russo, S., Knegtering, R.Bosch van den R.J. The specificity of neurological signs in schizophrenia: a review. Schizophr. Res 2000;43:109116.CrossRefGoogle Scholar
Buchanan, R.W., Heinrichs, D.W.The Neurological Evaluation Scale (NES): a structured instrument for the assessment of neurological signs in schizophrenia. Psychiatry Res 1989;27(3):335350.CrossRefGoogle Scholar
Cantor-Graae, E., Ismail, B., McNeil, T.F.Are neurological abnormalities in schizophrenic patients and their siblings the result of perinatal trauma?. Acta Psychiatr. Scand 2000;101(2):142147.CrossRefGoogle ScholarPubMed
Chen, E.Y., Hui, C.L., Chan, R.C., Dunn, E.L., Miao, M.Y., Yeung, W.S.et al.A 3-year prospective study of neurological soft signs in first-episode schizophrenia. Schizophr. Res 2005;75(1):4554.CrossRefGoogle ScholarPubMed
Chen, E.Y., Kwok, C.L., Au, J.W., Chen, R.Y., Lau, B.S.Progressive deterioration of soft neurological signs in chronic schizophrenic patients. Acta Psychiatr. Scand 2000;102(5):342349.CrossRefGoogle ScholarPubMed
Chen, E.Y., Shapleske, J., Luque, R., McKenna, P.J., Hodges, J.R., Calloway, S.P.et al.The Cambridge Neurological Inventory: a clinical instrument for assessment of soft neurological signs in psychiatric patients. Psychiatry Res 1995;56(2):183204.CrossRefGoogle ScholarPubMed
Emsley, R., Turner, H.J., Oosthuizen, P.P., Carr, J.Neurological abnormalities in first-episode schizophrenia: temporal stability and clinical and outcome correlates. Schizophr. Res 2005;75(1):3544.CrossRefGoogle ScholarPubMed
Ismail, B., Cantor Graae, E., McNeil, T.F.Neurological abnormalities in schizophrenic patients and their siblings. Am. J. Psychiatry 1998;155(1):8489.CrossRefGoogle ScholarPubMed
Kay, S.R., Fiszbein, A., Opler, L.A.The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull 1987;13(2):261276.CrossRefGoogle Scholar
Leask, S.J., Done, D.J., Crow, T.J.Adult psychosis, common childhood infections and neurological soft signs in a national birth cohort. Br. J. Psychiatry 2002;181:387392.CrossRefGoogle Scholar
Madsen, A.L., Vorstrup, S., Rubin, P., Larsen, J.K., Hemmingsen, R.Neurological abnormalities in schizophrenic patients: a prospective follow-up study 5 years after first admission. Acta Psychiatr. Scand 1999;100:119125.CrossRefGoogle ScholarPubMed
Smith, R.C., Hussain, M.I., Chowdhury, S.A., Stearns, A.Stability of neurological soft signs in chronically hospitalized schizophrenic patients. J. Neuropsychiatry Clin. Neurosci 1999;11(1):9196.CrossRefGoogle ScholarPubMed
Torrey, E.F.Neurological abnormalities in schizophrenic patients. Biol. Psychiatry 1980;15(3):381388.Google ScholarPubMed
Wing, J.K., Babor, T., Brugha, T., Burke, J., Cooper, J.E., Giel, R.et al.SCAN. Schedules for clinical assessment in neuropsychiatry. Arch. Gen. Psychiatry 1990;47(6):589593.CrossRefGoogle ScholarPubMed
Woods, B.T., Kinney, D.K., Yurgelun-Todd, D.A.Neurological “hard” signs and family history of psychosis in schizophrenia. Biol. Psychiatry 1991;30(8):806816.CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.