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Transmission of infectious drug resistance from animals to man

Published online by Cambridge University Press:  15 May 2009

D. M. Wells  and
O. B. James
D. M. Wells
Affiliation:
Department of Microbiology, University of the West Indies
O. B. James
Affiliation:
Department of Microbiology, University of the West Indies
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Summary

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The antibiotic resistance patterns of coliforms in faecal specimens from pigs and their human contacts were studied. The ability of the resistant coliforms to transfer their resistance in vitro to antibiotic-sensitive recipients was examined. The results showed that pigs which had received antibiotics carried more multiply-resistant, R-factor bearing coliforms than pigs which had not been given antibiotics. Human contacts of the antibiotic-treated pigs had a higher incidence of antibiotic-resistant coliforms with R-factors than human contacts of pigs which had not been given antibiotics. It is concluded that antibiotic treatment of farm, animals may lead to acquisition of antibiotic resistance by gut coliforms of man.

Type
Research Article
Information
Journal of Hygiene , Volume 71 , Issue 1 , March 1973 , pp. 209 - 215
Copyright
Copyright © Cambridge University Press 1973

References

REFERENCES

Anderson, E. S. & Lewis, M. J. (1965 a). Drug resistance and its transfer. Nature, Lond. 206, 579–83.CrossRefGoogle ScholarPubMed
Anderson, E. S. & Lewis, M. J. (1965 b). Characterisation of a transfer factor associated with drug transfer in Salmonella typhimurium. Nature, Lond. 208, 9.CrossRefGoogle ScholarPubMed
Anderson, E. S. (1968). The ecology of transferable drug resistance in the Enterobacteria. Annual Review of Microbiology, 22, 131–80.CrossRefGoogle ScholarPubMed
Bauer, A. W., Kirby, W. M. M., Sherris, J. C. & Turck, M. (1966). Antibiotic sensitivity testing by a standardized single disc method. American Journal of Clinical Pathology 45, 493–6.CrossRefGoogle Scholar
Datta, N. (1962). Transmissible drug resistance in an epidemic strain of Salmonella typhimurium. Journal of Hygiene 60, 301–10.CrossRefGoogle Scholar
Falkow, S., Citarella, J. A., Wohlheiter, J. A. & Watanabe, T. (1966). The molecular nature of R-factors. Journal of Molecular Biology 17, 102–16.CrossRefGoogle ScholarPubMed
Mann, P. G. & Gebedou, M. (1966). Infectious transfer of drug resistance between intestinal bacteria. Ethiopian Medical Journal 4, 181–8.Google Scholar
Maré, I. J. & Coetzee, J. N. (1965). The isolation of Enterobacteriaceae possessing the property of transmissible multiple-drug resistance. South African Medical Journal 39, 864–5.Google Scholar
Moorehouse, E. C., O'Grady, M. F. & O'Connor, H. (1969). Isolation from sausages of antibiotic-resistant Escherichia coli with R-factors. Lancet ii, 50–2.CrossRefGoogle Scholar
Ochiai, K., Yamanaxa, T., Kimura, K. & Sawada, O. (1959). Nippon Iji Shimpo 1861, 34–46. Quoted by Watanabe T. (1963). Infective heredity of multiple drug resistance in bacteria. Bacteriological Reviews 27, 87–115.Google Scholar
Schroeder, S., Terry, P. & Bennett, J. V. (1968). Antibiotic resistance and transfer factor in Salmonella, United States, 1967. Journal of the American Medical Association 205, 903–6.CrossRefGoogle ScholarPubMed
Smith, H. W. (1966). The incidence of infective drug resistance in strains of Escherichia coli isolated from diseased human beings and domestic animals. Journal of Hygiene 64, 465–74.Google ScholarPubMed
Smith, H. W. (1969 a). Transfer of antibiotic resistance from animal and human strains of Escherichia coli in the alimentary tract of man. Veterinary Record 85, 31–3.CrossRefGoogle ScholarPubMed
Smith, H. W. (1969 b). Transfer of antibiotic resistance from animal and human strains of Escherichia coli in the alimentary tract of man. Lancet i, 1174–6.CrossRefGoogle Scholar
Walton, J. R. (1966). Infectious drug resistance in Escherichia coli isolated from healthy farm animals. Lancet ii, 1300–2.CrossRefGoogle Scholar