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The titration of vaccinia virus on the chorio-allantoic membrane of the developing chick embryo

Published online by Cambridge University Press:  19 October 2009

J. C. N. Westwood ,
P. H. Phipps  and
E. A. Boulter
J. C. N. Westwood
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wilts
P. H. Phipps
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wilts
E. A. Boulter
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wilts
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A detailed investigation has been made of the pock-counting method for titrating vaccinia virus on embryonated eggs with a view to eliminating the wide scatter of results hitherto inseparable from the technique, and of assessing the precision of which it is capable. A detailed description is given of the technique evolved.

Reasons are given for supposing that the distribution of counts should follow the Poisson series, and considerable progress is claimed towards the achievement of such a distribution.

Type
Research Article
Information
Journal of Hygiene , Volume 55 , Issue 1 , March 1957 , pp. 123 - 139
Copyright
Copyright © Cambridge University Press 1957

References

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