Skip to main content Accessibility help
×
Home
Hostname: page-component-78bd46657c-gwmzn Total loading time: 0.183 Render date: 2021-05-06T07:53:45.069Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": false, "newCiteModal": false, "newCitedByModal": true }

A three-year diagnostic and epidemiological study on viral infantile diarrhoea in Rome

Published online by Cambridge University Press:  19 October 2009

G. Donelli
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
F. M. Ruggeri
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
A. Tinari
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
M. L. Marziano
Affiliation:
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome
D. Menichella
Affiliation:
Ospedale del Bambino Gesù, Piazza S. Onofrio 4, 00165 Rome
D. Caione
Affiliation:
Ospedale del Bambino Gesù, Piazza S. Onofrio 4, 00165 Rome
C. Concato
Affiliation:
Ospedale del Bambino Gesù, Piazza S. Onofrio 4, 00165 Rome
G. Rocchi
Affiliation:
Clinica Medica III, Università ‘La Sapienza’, Viale Regina Elena, 00161 Rome, Italy
S. Vella
Affiliation:
Clinica Medica III, Università ‘La Sapienza’, Viale Regina Elena, 00161 Rome, Italy
Rights & Permissions[Opens in a new window]

Summary

Rotavirus infection was demonstrated in 168 (29·3%) of 573 children hospitalized for acute diarrhoea in Rome between January 1982 and December 1984. Laboratory diagnosis of these infections was made by transmission electron microscopy and enzyme immunoassay techniques with an overall agreement of 91·3%. Astroviruses, adenoviruses and small round viruses were detected in the faeces of 36 patients (6·4%). Whereas in 1982 rotavirus positive patients were clustered in the winter and following spring, in the following years cases were recorded all year round. The median age of patients with rotavirus infections was 17, 10 and 11·5 months in 1982, 1983 and 1984, respectively. In addition, a smaller number of rotavirus positive cases were admitted in 1983 when compared to those admitted during the previous as well as the subsequent years. It is suggested that a herd immunity was induced in the population by epidemic spread of rotavirus in the first half of 1982.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1988

References

Albert, M. J. (1986). Enteric adenovirus. Archives of Virology 88, 117.CrossRefGoogle Scholar
Brandt, C. D., Kim, H. W., Rodriguez, W. J., Arrobio, J. O., Jeffries, B. C. & Parrott, R. H. (1982). Rotavirus gastroenteritis and weather. Journal of Clinical Microbiology 16, 478482.Google ScholarPubMed
Brandt, C. D., Kim, H. W., Rodriguez, W. J., Arrobio, J. O., Jeffries, B. C.Stallings, E. P., Lewis, C., Miles, A. J., Chanock, R. M., Kapikian, A. Z. & Parrott, R. H. (1983). Pediatric viral gastroenteritis during eight years of study. Journal of Clinical Microbiology 18, 7178.Google Scholar
Brandt, C. D., Kim, H. W., Yolken, R. H., Kapikian, A. Z., Arrobio, J. O., Rodriguez, W. J., Wyatt, R. G., Chanock, R. M. & Parrott, R. H. (1979). Comparative epidemiology of two rotavirus serotypes and other viral agents associated with pediatric gastroenteritis. American Journal of Epidemiology 110, 243254.CrossRefGoogle ScholarPubMed
Bryden, A. S., Davies, H. A., Hadley, R. E., Flewett, T. H., Morris, C. A. & Oliver, P. (1975). Rotavirus enteritis in the West Midlands during 1974. Lancet ii, 241243.CrossRefGoogle Scholar
Caul, E. O., Paver, W. K. & Clarke, S. K. R. (1975). Coronavirus particles in faeces from patients with gastroenteritis. Lancet i, 1192.CrossRefGoogle Scholar
Cukor, G. & Blacklow, N. R. (1984). Human viral gastroenteritis. Microbiological Reviews 48, 157179.Google ScholarPubMed
Flewett, T. H., Bryden, A. S. & Davies, H. (1974). Diagnostic electron microscopy of faeces. I. The viral flora of the faeces as seen by electron microscopy. Journal of Clinical Pathology 27, 603614.CrossRefGoogle ScholarPubMed
Hammond, G. W., Ahluwalia, G. S., Barker, F. G., Horsman, G. & Hazelton, P. R. (1982). Comparison of direct and indirect enzyme immunoassays with direct ultracentrifugation before electron microscopy for detection of rotaviruses. Journal of Clinical Microbiology 16, 5359.Google ScholarPubMed
Herring, A. J., Inglis, N. F., Ojeh, C. K., Snodgrass, D. R. & Menzies, J. D. (1982). Rapid diagnosis of rotavirus infection by direct detection of viral nucleic acid in silver-stained polyacrylamidc gels. Journal of Clinical Microbiology 16, 473477.Google ScholarPubMed
Kapikian, A. Z., Greenberg, H. B., Wyatt, R. G., Kalica, A. R. & Chanock, R. M. (1982). The Norwalk group of viruses. Agents associated with epidemic viral gastroenteritis. In Virus Infections of the Gastrointestinal Tract (ed. Tyrrell, D. A. J. & Kapikian, A. Z.), pp. 147177. New York Basel: Marcel Dekkcr, Inc.Google Scholar
Kapikian, A. Z., Kim, H. W., Wyatt, R. G., Cline, W. L., Arrobio, J. O., Brandt, C. D., Rodriguez, W. J., Sack, D. A., Chanock, R. M. & Parrott, R. H. (1970). Human rcoviruslike agent as tho major pathogen associated with ‘winter’ gastroenteritis in hospitalized infants and young children. New England Journal of Medicine 294, 965972.CrossRefGoogle Scholar
Konno, T., Suzuki, H., Tmai, A., Kutsuzawa, T., Ishida, N., Katsushima, N., Sakamoto, M., Kitaoka, S., Tsuboi, R. & Adachi, M. (1978). A long-term survey of rotavirus infection in Japanese children with acute gastroenteritis. Journal of Infectious Diseases 138, 569570.Google ScholarPubMed
Konno, T., Suzuki, H., Katsushima, N., Imai, A., Tazawa, F., Kutsuzawa, T., Kitaoka, S., Sakamoto, M., Yazaki, N. & Ishida, N. (1983). Influence of temperature and relative humidity on human rotavirus infection in Japan. Journal of Infectious Diseases 147, 125128.CrossRefGoogle ScholarPubMed
Laemmli, U. K. (1970). Cleavage of structural proteins during tho assembly of tho head of bacteriophago T4. Nature 227, 680685.CrossRefGoogle Scholar
Madeley, C. R. & Cosgrove, B. P. (1975). 28 nm particles in faeces in infantile gastroenteritis. Lancet ii, 451452.CrossRefGoogle Scholar
Madeley, C. R. & Cosgrove, B. P. (1976). Caliciviruses in man. lancet i, 199200.CrossRefGoogle Scholar
Madeley, C. R., Cosgrove, B. P., Bell, E. J. & Fallon, R. J. (1977). Stool viruses in babies in Glasgow. 1. Hospital admissions with diarrhoea. Journal of Hygiene 78, 261273.CrossRefGoogle Scholar
Middleton, P. J., Szymanski, M. T. & Petric, M. (1977). Viruses associated with acute gastroenteritis in young children. American Journal of Diseases of Children 131, 733737.Google ScholarPubMed
Miotti, P. G., Eiden, J. & Yolken, R. H. (1985). Comparative efficiency of commercial immunoassays for tho diagnosis of rotavirus gastroenteritis during tho course of infection. Journal of Clinical Microbiology 22, 693698.Google Scholar
Monto, A. S. & Koopman, J. S. (1980). The Tecumsch study. XI. Occurrence of acute enteric illness in the community. American Journal of Epidemiology 112, 323333.CrossRefGoogle Scholar
Riepenhoff-Talty, M., Saif, L. J., Barrett, H. J., Suzuki, H. & Ogra, P. L. (1983). Potential spectrum of etiological agents of viral enteritis in hospitalized infants. Journal of Clinical Microbiology 17, 352356.Google ScholarPubMed
Snyder, J. D. & Merson, M. H. (1982). The magnitude of the global problem of acute diarrhoeal disease: a review of active surveillance data. Bulletin of the World Health Organisation 60, 605613.Google ScholarPubMed
Steering Committee of the Scientific Working Group on Viral Diarrhoeas, Who Programme for Diarrhoeal Diseases Control (1984). Nomenclature of human rotaviruses: designation of subgroups and serotypes. Bulletin of the World Health Organization 62, 501503.Google Scholar
Tufvesson, B. & Johnsson, T. (1976). Occurrence of reo-like viruses in young children with acute gastroenteritis. Ada Pathologica Microbiologica Scandinavica. Sect. B 84, 2228.Google ScholarPubMed
Uhnoo, I., Wadell, G., Svensson, L. & Johansson, M. E. (1984). Importance of enteric adenoviruses 40 and 41 in acute gastroenteritis in infants and young children. Journal of Clinical Microbiology 20, 365372.Google ScholarPubMed
Who Scientific Working Group (1980). Rotavirus and other viral diarrhoeas. Bulletin of the World Health Organization 58, 183198.Google Scholar
You have Access

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

A three-year diagnostic and epidemiological study on viral infantile diarrhoea in Rome
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

A three-year diagnostic and epidemiological study on viral infantile diarrhoea in Rome
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

A three-year diagnostic and epidemiological study on viral infantile diarrhoea in Rome
Available formats
×
×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *