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Studies on poliomyelitis virus: III. The use of ultra-violet light as an additional means of inactivation of formalinized vaccine

Published online by Cambridge University Press:  15 May 2009

J. W. F. Hampton  and
A. Polson
J. W. F. Hampton
Affiliation:
Laboratories of the Poliomyelitis Research Foundation, Johannesburg, and the Council for Scientific and Industrial Research and University of Capetown Virus Research Unit, University of Capetown
A. Polson
Affiliation:
Laboratories of the Poliomyelitis Research Foundation, Johannesburg, and the Council for Scientific and Industrial Research and University of Capetown Virus Research Unit, University of Capetown
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The inactivation rates of tissue-culture polio virus have been determined and these have been applied to the irradiation of formalinized vaccine, as an additional inactivation process, using a simple irradiator.

The antigenic potency of the vaccine was apparently unimpaired.

We wish to thank the late Prof. van den Ende for his keen interest and criticism; Dr H. Malherbe and his staff for carrying out many of the titrations; Dr P. D. Winter for co-operation in irradiating samples of vaccine, and Margaret Pakes for invaluable technical assistance.

Type
Research Article
Information
Journal of Hygiene , Volume 56 , Issue 2 , June 1958 , pp. 266 - 270
Copyright
Copyright © Cambridge University Press 1958

References

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