Sorbitol-fermenting Shiga toxin-producing Escherichia coli O157: indications for an animal reservoir

D. ORTH; K. GRIF; M. P. DIERICH; R. WÜRZNER

doi:10.1017/S0950268805005467

Abstract

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This study investigates a sorbitol-fermenting enterohaemorrhagic Escherichia coli (SF EHEC) O157 infection in a farmer's family in the Austrian province of Salzburg. The investigation commenced after a 10-month-old boy was admitted to hospital with the clinical diagnosis of a haemolytic–uraemic syndrome (HUS) and his stool specimen grew SF EHEC O157:H−. In a subsequent environmental survey, a stool specimen of the 2-year-old brother and faecal samples of two cattle from the family's farm were also found to be positive for SF EHEC O157:H−. All four isolates had indistinguishable phenotypic and molecular characteristics and were identical to the first strain detected in Bavaria in 1988. Despite identical isolates being demonstrated in Bavaria after 1988, and until this report, increased surveillance in neighbouring Austria had not found this organism. We propose that the strain may have recently spread from Bavaria to Austria. Although SF EHEC O157:H− strains are still rare, they may represent a considerable health threat as they can spread from farm animals to humans and between humans.

Crossref Citations

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Orth, Dorothea Grif, Katharina Dierich, Manfred P. and Würzner, Reinhard 2006. Cytolethal distending toxins in Shiga toxin-producing Escherichia coli: alleles, serotype distribution and biological effects. Journal of Medical Microbiology, Vol. 55, Issue. 11, p. 1487.

Orth, Dorothea Grif, Katharina Dierich, Manfred P. and Würzner, Reinhard 2006. Prevalence, structure and expression of urease genes in Shiga toxin-producing Escherichia coli from humans and the environment. International Journal of Hygiene and Environmental Health, Vol. 209, Issue. 6, p. 513.

Friedrich, A. W. Zhang, W. Bielaszewska, M. Mellmann, A. Kock, R. Fruth, A. Tschape, H. and Karch, H. 2007. Prevalence, Virulence Profiles, and Clinical Significance of Shiga Toxin-Negative Variants of Enterohemorrhagic Escherichia coli O157 Infection in Humans. Clinical Infectious Diseases, Vol. 45, Issue. 1, p. 39.

Orth, Dorothea Grif, Katharina Dierich, Manfred P. and Würzner, Reinhard 2007. Variability in tellurite resistance and the ter gene cluster among Shiga toxin-producing Escherichia coli isolated from humans, animals and food. Research in Microbiology, Vol. 158, Issue. 2, p. 105.

Rosser, Tracy Dransfield, Tracy Allison, Lesley Hanson, Mary Holden, Nicola Evans, Judith Naylor, Stuart La Ragione, Roberto Low, J. Christopher and Gally, David L. 2008. Pathogenic Potential of Emergent Sorbitol-Fermenting Escherichia coli O157:NM . Infection and Immunity, Vol. 76, Issue. 12, p. 5598.

Duffy, G. Lynch, O.A. and Cagney, C. 2008. Tracking emerging zoonotic pathogens from farm to fork. Meat Science, Vol. 78, Issue. 1-2, p. 34.

Müsken, Anne Bielaszewska, Martina Greune, Lilo Schweppe, Christian H. Müthing, Johannes Schmidt, Herbert Schmidt, M. Alexander Karch, Helge and Zhang, Wenlan 2008. Anaerobic Conditions Promote Expression of Sfp Fimbriae and Adherence of Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:NM to Human Intestinal Epithelial Cells . Applied and Environmental Microbiology, Vol. 74, Issue. 4, p. 1087.

Orth, Dorothea Grif, Katharina Zimmerhackl, Lothar Bernd and Würzner, Reinhard 2008. Prevention and treatment of enterohemorrhagicEscherichia coliinfections in humans. Expert Review of Anti-infective Therapy, Vol. 6, Issue. 1, p. 101.

Mellmann, Alexander Lu, Shan Karch, Helge Xu, Jian-guo Harmsen, Dag Schmidt, M. Alexander and Bielaszewska, Martina 2008. Recycling of Shiga Toxin 2 Genes in Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:NM . Applied and Environmental Microbiology, Vol. 74, Issue. 1, p. 67.

Mellmann, Alexander Bielaszewska, Martina and Karch, Helge 2009. Intrahost Genome Alterations in Enterohemorrhagic Escherichia coli. Gastroenterology, Vol. 136, Issue. 6, p. 1925.

ALPERS, K. WERBER, D. FRANK, C. KOCH, J. FRIEDRICH, A. W. KARCH, H. AN DER HEIDEN, M. PRAGER, R. FRUTH, A. BIELASZEWSKA, M. MORLOCK, G. HEISSENHUBER, A. DIEDLER, A. GERBER, A. and AMMON, A. 2009. Sorbitol-fermenting enterohaemorrhagicEscherichia coliO157:H−causes another outbreak of haemolytic uraemic syndrome in children. Epidemiology and Infection, Vol. 137, Issue. 3, p. 389.

Buvens, G. Piérard, D. Hachimi-Idrissi, S. and Lauwers, S. 2009. FIRST SORBITOL-FERMENTING VEROCYTOTOXIN-PRODUCINGESCHERICHIA COLIO157: H- ISOLATED IN BELGIUM. Acta Clinica Belgica, Vol. 64, Issue. 1, p. 59.

Stephan, Roger Zhang, Wenlan Bielaszewska, Martina Mellmann, Alexander and Karch, Helge 2009. Phenotypic and Genotypic Traits of Shiga Toxin–NegativeE. coliO157:H7/H−Bovine and Porcine Strains. Foodborne Pathogens and Disease, Vol. 6, Issue. 2, p. 235.

Orth, Dorothea Grif, Katharina Zimmerhackl, Lothar Bernd and Würzner, Reinhard 2009. Sorbitol-fermenting Shiga toxin-producing Escherichia coli O157 in Austria. Wiener klinische Wochenschrift, Vol. 121, Issue. 3-4, p. 108.

Bono, J. L. Smith, T. P. L. Keen, J. E. Harhay, G. P. McDaneld, T. G. Mandrell, R. E. Jung, W. K. Besser, T. E. Gerner-Smidt, P. Bielaszewska, M. Karch, H. and Clawson, M. L. 2012. Phylogeny of Shiga Toxin-Producing Escherichia coli O157 Isolated from Cattle and Clinically Ill Humans. Molecular Biology and Evolution, Vol. 29, Issue. 8, p. 2047.

Rosales, Alejandra Hofer, Johannes Zimmerhackl, Lothar-Bernd Jungraithmayr, Therese C. Riedl, Magdalena Giner, Thomas Strasak, Alexander Orth-Höller, Dorothea Würzner, Reinhard and Karch, Helge 2012. Need for Long-term Follow-up in Enterohemorrhagic Escherichia coli–Associated Hemolytic Uremic Syndrome Due to Late-Emerging Sequelae. Clinical Infectious Diseases, Vol. 54, Issue. 10, p. 1413.

Sallam, Khalid Ibrahim Mohammed, Mahmoud Ahmed Ahdy, Asmaa Mohammed and Tamura, Tomohiro 2013. Prevalence, genetic characterization and virulence genes of sorbitol-fermenting Escherichia coli O157:H- and E. coli O157:H7 isolated from retail beef. International Journal of Food Microbiology, Vol. 165, Issue. 3, p. 295.

King, L.A. Loukiadis, E. Mariani-Kurkdjian, P. Haeghebaert, S. Weill, F.-X. Baliere, C. Ganet, S. Gouali, M. Vaillant, V. Pihier, N. Callon, H. Novo, R. Gaillot, O. Thevenot-Sergentet, D. Bingen, E. Chaud, P. and de Valk, H. 2014. Foodborne transmission of sorbitol-fermenting Escherichia coli O157:[H7] via ground beef: an outbreak in northern France, 2011. Clinical Microbiology and Infection, Vol. 20, Issue. 12, p. O1136.

Karch, Helge Ammon, Andrea Tarr, Phillip I. and Bielaszewska, Martina 2014. Population Genetics of Bacteria. p. 273.

Koutsoumanis, K.P. Lianou, A. and Sofos, J.N. 2014. Encyclopedia of Agriculture and Food Systems. p. 250.

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Sorbitol-fermenting Shiga toxin-producing Escherichia coli O157: indications for an animal reservoir

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