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The size of airborne dust particles precipitating bronchospasm in house dust sensitive children

Published online by Cambridge University Press:  15 May 2009

R. P. Clark
Affiliation:
Division of Hospital Infection, Clinical Research Centre, Harrow
T. D. Preston
Affiliation:
Medical Computer Centre, Westminster Hospital, London SW 1
D. C. Gordon-Nesbitt
Affiliation:
Department of Paediatrics, Royal National Throat, Nose and Ear Hospital, London, WC 1, and St Stephen's Hospital, Fuiham Road, London, SW 10
S. Malka
Affiliation:
Department of Paediatrics, Royal National Throat, Nose and Ear Hospital, London, WC 1, and St Stephen's Hospital, Fuiham Road, London, SW 10
L. Sinclair
Affiliation:
Department of Paediatrics, Royal National Throat, Nose and Ear Hospital, London, WC 1, and St Stephen's Hospital, Fuiham Road, London, SW 10
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Summary

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We have assessed the effect of house-cleaning procedures on changes in airborne dust and bacteria counts and correlated these with respiratory function tests in 14 children with bronchial asthma who were known to have developed attacks at home, and who had positive skin tests to house dust and the house-dust mite.

We have demonstrated that after cleaning procedures a positive and statistically significant correlation exists between the increase in the numbers of small particles, 2 μm. and less in diameter, in the environment, and reduction in mean peak flow. This indicates that particles of this size penetrate the bronchial tree and are the causative factor in the genesis of bronchospasm.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1976

References

REFERENCES

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