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A serosurvey for HTLV-I among high-risk populations and normal adults in Egypt

Published online by Cambridge University Press:  15 May 2009

N. T. Constantine ,
M. Fathi Sheba ,
A. L. Corwin ,
R. S. Danahy ,
J. D. Callahan  and
D. M. Watts
N. T. Constantine
Affiliation:
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt Department of Pathology, University of Maryland, Baltimore, MD, USA
M. Fathi Sheba
Affiliation:
Ministry of Health, Arab Republic of Egypt
A. L. Corwin
Affiliation:
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt
R. S. Danahy
Affiliation:
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt
J. D. Callahan
Affiliation:
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt
D. M. Watts
Affiliation:
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt
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The prevalence of antibodies to human T-cell lymphotropic virus type I (HTLV-1) was determined in high-risk groups and normal adults in Egypt. Among 647 individuals tested, 6 (0·9%) were confirmed positive by western blot analysis. These included 2 (0·7%) of 279 drug addicts, 1 (3·3%) of 30 patients with sexually transmitted diseases, and 3 (2·2%) of 133 healthy individuals. Antibody was not detected in 47 blood recipients or 158 prostitutes. There was no correlation between sex or geographical location and HTLV-I infection. Fifty-three of the 647 sera (8%) were initially reactive by ELISA, but only 12 sera were repeatedly reactive. Since only 4 of these repeatedly reactive sera were confirmed by the western blot, the frequency of false positives using the DuPont screening ELISA was 1·2% (8/643). Two additional sera, confirmed positive by western blot, had been reactive, but not repeatedly, by ELISA. In comparison to the prevalence of HTLV-I antibody among risk groups in many parts of the world, the prevalence in Egypt was low.

Type
Research Article
Information
Epidemiology & Infection , Volume 107 , Issue 2 , October 1991 , pp. 429 - 433
Copyright
Copyright © Cambridge University Press 1991

References

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