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Paralytic poliomyelitis in England & Wales, 1970–84

Published online by Cambridge University Press:  19 October 2009

N. T. Begg ,
R. Chamberlain  and
M. Roebuck
N. T. Begg
Affiliation:
PHLS Communicable Disease Surveillance Centre, 61 Colindale Avenue, London NW9 5EQ
R. Chamberlain
Affiliation:
Formerly of the Epidemiology Research Laboratory, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT
M. Roebuck
Affiliation:
Formerly of the Virus Reference Laboratory, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT
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Summary

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In 1962 the Public Health Laboratory Service (PHLS) became responsible for the Poliomyelitis Surveillance Scheme for England and Wales, which since 1970 has included the World Health Organisation (WHO) enquiry into Acute Persisting Spinal Paralysis. All the records have been kept, including those of patients who were later considered not to have had poliomyelitis. This paper reviews the cases between 1970–84 of patients normally resident in England and Wales, where the clinical features of the illness were considered by the clinician in charge to be those of poliomyelitis and in which either poliovirus was isolated or there was serological evidence of recent infection. Seventy cases met these criteria. Two patients died. A wild strain of poliovirus was isolated in 19 cases; a vaccine-like strain in 27; an intermediate strain in 5; and in 19 cases the strain was not known or there was no isolate. Eleven patients had a history of overseas travel; 17 had been vaccinated recently; and 12 had been in contact with a recent vaccinee. In the remaining 30 cases, the source of the infection was not found. Other details, including the age distribution, vaccination history and the laboratory findings are discussed.

Type
Research Article
Information
Epidemiology & Infection , Volume 99 , Issue 1 , August 1987 , pp. 97 - 106
Copyright
Copyright © Cambridge University Press 1987

References

REFERENCES

Collingham, K. E., Pollock, T. M. & Roebuck, M. O. (1978). Paralytic poliomyelitis in Englnnd and Wales 1976–77. Lancet i, 976–977.Google Scholar
Geffen, T. J. & Spicer, C. C. (1960). Poliomyelitis in the vaccinated. England and Wales, 1958. Lancet ii, 87–89.Google Scholar
Miller, D. L. & Galbraith, N. S. (1965). Surveillance of the safety of oral poliomyelitis vaccine in Englnnd and Wales 1962–4. British Medical Journal 2, 504–509.Google Scholar
Miller, D. L., Reid, D. & Diamond, J. R. (1970). Poliomyelitis surveillance in England and Wales, 1965–8. Public Health (tendon) 84, 265–285.Google Scholar
Roebuck, M. & Chamberlain, R. (1982). Prevalence of antibodies to poliovirus in 1978 among subjects aged 0–88 years. British Medical Journal 284, 697–700.Google Scholar
Smith, J. W. G. & Wherry, P. J. (1978). Poliomyelitis surveillance in England and Wales, 1969–1975. Journal of Hygiene 80, 155–167.CrossRefGoogle ScholarPubMed
Van Wezel, A. L. & Hazendonk, A. G. (1978). Intratypic serodiflerentiation of poliomyelitis virus strains by strain specific antisera. Intervirology 11, 2–8.Google Scholar
WHO Consultative Group (1982). The relationship between acute persisting spinal paralysis and poliomyelitis vaccine – results of a ten-year enquiry. Bulletin of the World Health Organization 60, 231–242.Google Scholar