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Occurrence of FIme plasmids in multiply antimicrobial-resistant Escherichia coli isolated from urinary tract infection

Published online by Cambridge University Press:  15 May 2009

P. A. Riley ,
E. J. Threlfall ,
T. Cheasty ,
K. G. Wooldridge ,
P. H. Williams  and
I. Phillips
P. A. Riley
Affiliation:
Department of Microbiology, United Medical and Dental Schools, St Thomas's Hospital, London SE1 7EH
E. J. Threlfall
Affiliation:
Laboratory of Enteric Pathogens, Central Public Health Laboratory, 6I Colindale Avenue, London NW9 5HT
T. Cheasty
Affiliation:
Laboratory of Enteric Pathogens, Central Public Health Laboratory, 6I Colindale Avenue, London NW9 5HT
K. G. Wooldridge
Affiliation:
Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH
P. H. Williams
Affiliation:
Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH
I. Phillips
Affiliation:
Department of Microbiology, United Medical and Dental Schools, St Thomas's Hospital, London SE1 7EH
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Plasmids belonging to the FIme incompatibility group were found in seven different serogroups of multiply antimicrobial-resistant Escherichia coli isolated from patients with urinary tract infection (UTI) and living in south-east London. Although widespread in Salmonella spp., FIme plasmids have only previously been described in E. coli in a strain of serogroup O15 K52 H1 responsible for an extensive and protracted outbreak of invasive community-acquired infection in south-east London in 1986. Our findings suggest either a wider background occurrence of FIme plasmids in E. coli associated with UTI than previously reported or alternatively, the dissemination and subsequent molecular diversification of the FIme plasmid associated with the epidemic strain of serogroup O15 K52 H1.

Type
Research Article
Information
Epidemiology & Infection , Volume 110 , Issue 3 , June 1993 , pp. 459 - 468
Copyright
Copyright © Cambridge University Press 1993

References

REFERENCES

1.Eykyn, SJ. Phillips, I. Community-acquired outbreak of multiresistant invasive Escherichia coli infection. Lancet 1986: ii: 1454.CrossRefGoogle Scholar
2.Phillips, I. Eykyn, SJ. King, A. Grandsen, WR. Rowe, B. Frost, JA. Gross, RJ. Epidemic multiresistant Escherichia coli infection in West Lambeth Health District. Lancet 1988: ii: 1338–41.Google Scholar
3.Threlfall, EJ. Carr, JM. Anderson, ES. Compatibility relations of resistance plasmids in Salmonella typhimurium of Middle Eastern origin. Proc Soc Gen Microbiol 1976: 3: 88.Google Scholar
4.Anderson, ES. Threlfall, EJ. Carr, JM, McConnell, MM. Smith, HR. Clonal distribution of resistance plasmid-carrying Salmonella typhimurium. mainly in the Middle East. J Hyg 1977: 79: 425–48.CrossRefGoogle ScholarPubMed
5.McConnell, MM. Smith, HR. Leonardopoulos, J. Anderson, ES. The value of plasmid studies in the epidemiology of infections due to drug-resistant Salmonella wien. J Infect Dis 1979: 159: 178–90.CrossRefGoogle Scholar
6.Frost, JA. Rowe, B. Ward, LR. Threlfall, EJ. Characterization of resistance plasmids and carried phages in an epidemic clone of multi-resistant Salmonella typhimurium in India. J Hyg 1982: 88: 193–204.CrossRefGoogle Scholar
7.Rowe, B. Threlfall, EJ. Ward, LR. Does choloramphenicol remain the drug of choice for typhoid? Epidemiol Infect 1987; 98: 379–83.CrossRefGoogle Scholar
8.Brown, DJ. Threlfall, EJ. Rowe, B. Instability of multiple drug resistance plasmids in Salmonella typhimurium isolated from poultry. Epidemiol Infect 1991: 106: 247–57.CrossRefGoogle ScholarPubMed
9.Brown, D. Blowers, R. Disc methods of sensitivity testing and other semi-quantitative methods. In: Reeves, DS. Phillips, I. Williams, JD. Wise, R, eds. Laboratory methods in antimicrobial chemotherapy. Edinburgh: Churchill Livingstone, 1974: 8–30.Google Scholar
10.Ørskov, F. Ørskov, I. Escherichia coli O: H serotypes isolated from human blood: prevalence of K1 antigen with technical details of O and H antigenic determination. Acta Path Microbiol Scand 1975: 83: 595–600.Google Scholar
11.Anderson, ES. Threlfall, EJ. The characterization of plasmids in the enterobacteria. J Hyg 1974: 72: 471–87.CrossRefGoogle ScholarPubMed
12.Grindley, NDF. Grindley, JN, Anderson, ES. R factor compatibility groups. Mol Gen Genet 1972: 119: 287–97.CrossRefGoogle ScholarPubMed
13.Jacob, AE. Shapiro, JA. Yamamoto, L. Smith, DI. Cohen, SN, Berg, D. Appendix, B: bacterial plasmids. In: Bukhari, AI. Shapiro, JA. Adhya, SL, eds. DNA insertion elements. plasmids and episomes. Cold Spring Harbor Laboratory, 1977: 607–70.Google Scholar
14.Kado, CI. Liu, S-T. Rapid procedure for detection and isolation of large and small plasmids. J Bacteriol 1981; 145: 1365–73.CrossRefGoogle ScholarPubMed
15.Threlfall, EJ. Rowe, B. Ward, LR. Subdivision of Salmonella enteritidis phage types by plasmid profile typing. Epidemiol Infect 1989; 102: 459–65.CrossRefGoogle ScholarPubMed
16.Threlfall, EJ. Rowe, B. Ferguson, JL. Ward, LR. Characterization of plasmids conferring resistance to gentamicin and apramycin in strains of Salmonella typhimurium phage type 204c isolated in Britain. J Hyg 1986; 97: 419–26.CrossRefGoogle ScholarPubMed
17.Olsen, JE. An improved method for the rapid isolation of plasmid DNA from wild-type gram-negative bacteria for plasmid restriction profile analysis. Lett Appl Microbiol 1990; 10: 209–12.CrossRefGoogle ScholarPubMed
18.Dice, LR. Measures of the amount of ecologic association between species. Ecology 1945; 26: 297–302.CrossRefGoogle Scholar
19.Carbonetti, NH. Williams, PH. Detection of synthesis of the hydroxamate siderophore aerobactin by pathogenic isolates of Escherichia coli. In: Sussman, M. ed. The virulence of E. coli; reviews and methods. London: Academic Press, 1985: 419–24.Google Scholar
20.Roberts, RB, Abelson, PH. Cowe, DB. Bolton, ET, Britten, RJ. Studies of biosynthesis in E. coli. Publication 607. Washington: Carnegie Institute of Washington, 1955: 5.Google Scholar
21.Grunstein, M, Hogness, DS. Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. Proc Nat Acad Sci USA 1975; 72: 3961–5.CrossRefGoogle ScholarPubMed
22.Feinberg, AP. Vogelstein, B. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Addendum. Anal Biochem 1984; 137: 266–7.Google ScholarPubMed
23.Bindereif, A, Neilands, JB. Cloning of the aerobactin-mediated iron assimilation system of plasmid CoIV. J Bacteriol 1983; 153: 1111–3.CrossRefGoogle Scholar
24.Carbonetti, NH, Williams, PH. A cluster of five genes specifying the aerobactin iron uptake system of plasmid CoIV-K30. Infect Immun 1984; 46: 7–12.CrossRefGoogle Scholar
25.Carbonetti, NH, Boonchai, S, Parry, SH, Väisänen-Rhen, V, Korhonen, TK, Williams, PH. Aerobactin-mediated iron uptake by Escherichia coli isolates from human extraintestinal infections. Infect Immun 1986; 51: 966–8.CrossRefGoogle ScholarPubMed
26.Rowe, B, Threlfall, EJ. Drug resistance in gram-negative aerobic bacilli. Brit Med Bull 1984: 40: 68–76.CrossRefGoogle ScholarPubMed
27.Colonna, B, Nicoletti, M, Visca, P, Casalino, M, Valenti, P, Maimone, F. Composite ISI elements encoding hydroxamate-mediated iron uptake in FIme plasmids from epidemic Salmonella spp. J Bacteriol 1985; 162: 307–16.CrossRefGoogle Scholar
28.Willshaw, GA, Smith, HR, Anderson, ES. Molecular studies of FIme plasmids, particularly in epidemic Salmonella typhimurium. Molec Gen Genet 1978; 159: 111–6.CrossRefGoogle ScholarPubMed
29.Chau, PY, Ling, J, Threlfall, EJ. Im, SKN. Genetic instability of R plasmids in relation to the shift of drug resistance in Salmonella johannesburg. J Gen Microbiol 1982; 128: 239–45.Google Scholar
30.Casalino, M, Comanducci, A, Nicoletti, M, Maimone, F. Stability of plasmid content in Salmonella wien in late phases of the epidemic history. Antimicrob Ag Chemother 1984; 25: 499–501.CrossRefGoogle ScholarPubMed