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Natural infection with influenza A (H3N2). The development, persistence and effect of antibodies to the surface antigens

Published online by Cambridge University Press:  15 May 2009

A. J. Smith
Affiliation:
Public Health Laboratory, St Luke's Hospital, Guildford, GU1 3NT, Surrey
Joan R. Davies
Affiliation:
Public Health Laboratory, St Luke's Hospital, Guildford, GU1 3NT, Surrey
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Summary

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A technique for estimating antibodies to the neuraminidase antigens of influenza A is described.

The antibody response to the haemagglutinin and neuraminidase antigens of influenza A (H3N2) was studied in a boys' public school over the four-year period 1970–4. During this time there were two outbreaks of influenza A and the effect of antibody on the result of natural challenge was investigated. No boy who had homotypic neuraminidase antibody had clinical influenza.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1976

References

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