Hostname: page-component-8448b6f56d-c47g7 Total loading time: 0 Render date: 2024-04-25T06:23:58.338Z Has data issue: false hasContentIssue false

Iron in Human Nutrition

Published online by Cambridge University Press:  15 May 2009

E. M. Widdowson
Affiliation:
From the Biochemical Department, King's College Hospital, London
R. A. McCance
Affiliation:
From the Biochemical Department, King's College Hospital, London
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

An investigation has been made of the iron intake of sixty-three men and sixty-three women of the English middle class, living on freely chosen diets. Their intakes of total iron have been found to have mean values of 16·8 and 11·4 mg. per day respectively. The highest value found for any woman was only just above the average for the men, and 30 per cent, of the women were taking less than 10 mg. of iron a day.

“Available” or inorganic iron in the diets has also been calculated, and has been found to average 10·8 mg. per day for men and 7·9 mg. for women. If fairly large amounts of meat are eaten, the available iron may be less than half the total iron in the diet. If, on the other hand, the diet is mainly vegetarian, about 90 per cent, of the total iron may be available.

Haemoglobin determinations were made on more than 50 per cent, of the subjects. The men's average was 102 per cent, and the women's 93 per cent. No significant correlation could be found between the total or available iron intake and the haemoglobin level.

The effect of large doses of iron (100 mg. of iron a day as ferrous sulphate or ferric ammonium citrate) on normal haemoglobin levels has been investigated. This has scarcely altered the haemoglobin percentages of men, but has increased the values for women by 4–17 per cent, and a mean rise of over 10 per cent, has been observed.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1936

References

REFERENCES

Cathcart, E. P. and Murray, A. M. T. (1931). Med. Res. Council, Special Report Series, No. 151.Google Scholar
Davidson, L. S. P., Fullerton, H. W. et al. (1933). Brit. Med. J. i, 685.CrossRefGoogle Scholar
Elvehjem, C. A., Hart, E. B. and Sherman, W. C. (1933). J. Biol. Chem. 103, 61.CrossRefGoogle Scholar
Farrar, G. E. and Goldhamer, S. M. (1935). J. Nutrition, 10, 241.CrossRefGoogle Scholar
Gillett, L. H. (1918). Amer. J. Physiol. 47, 25.CrossRefGoogle Scholar
Hawley, E. (1927). U.S. Dept. Agric. Tech. Bull. No. 8, Washington.Google Scholar
Hawley, E. (1929). U.S. Dept. Agric. Circular, No. 89.Google Scholar
Lintzel, W. (1929). Z.f. Biol. 89, 342 and 350.Google Scholar
McCance, R. A. and Shipp, H. L. (1933). Med. Res. Council, Special Report Series, No. 187.Google Scholar
Mccance, R. A., Widdowson, E. M. and Shackleton, L. R. B. (1936). Med. Res. Council, Special Report Series (in press).Google Scholar
McKay, H. (1929). Ohio Agric. Exp. Sta. Bull. No. 433.Google Scholar
Mitchell, H. (1935). J. Amer. Diet. Ass. 11, 28.CrossRefGoogle Scholar
Ohlson, M. A. and Daum, K. (1935). J. Nutrition, 9, 75.CrossRefGoogle Scholar
Orr, J. B. and Clark, M. L. (1930). Lancet, ii, 594.CrossRefGoogle Scholar
Price-Jones, C. (1931). J. Path. and Bact. 34, 779.CrossRefGoogle Scholar
Shackleton, L. R. B. and McCance, R. A. To be Published.Google Scholar
Sherman, H. C. (1907). U.S. Office of Expt. Sta. Bull. No. 185.Google Scholar
Sherman, H. C. (1933 a). Chemistry of Food and Nutrition, 4th ed.Google Scholar
Sherman, H. C. (1933 b). Food Products, 3rd ed.Google Scholar
Sherman, H. C., Elvehjem, C. A. and Hart, E. B. (1934). J. Biol. Chem. 107, 133.Google Scholar
Sherman, H. C. and Gillett, L. H. (1917). New York Assoc. for Improving the Condition of the Poor. Publ. 121.Google Scholar
Sherman, H. C., Mettler, A. J. and Sinclair, J. E. (1910). U.S. Dept. of Agric. Expt. Sta. Bull. No. 227.Google Scholar
Stockman, R. and Greig, E. D. W. (1897). J. Physiol. 21, 55.CrossRefGoogle Scholar
Von Wendt, G. (1905). Skand. Archiv f. Physiol. 17, 211.CrossRefGoogle Scholar
Widdowson, E. M. To be published.Google Scholar