Hostname: page-component-7479d7b7d-m9pkr Total loading time: 0 Render date: 2024-07-08T13:54:18.070Z Has data issue: false hasContentIssue false
  • English
  • Français

Invasive group B streptococcal disease in infants: a 19-year nationwide study. Serotype distribution, incidence and recurrent infection

Published online by Cambridge University Press:  16 November 2004

K. EKELUND  and
H. B. KONRADSEN
K. EKELUND
Affiliation:
Streptococcus Unit, Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark
H. B. KONRADSEN
Affiliation:
Streptococcus Unit, Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

During the period 1984–2002, 472 cases of invasive group B streptococcal (GBS) disease in infants aged 0–90 days in Denmark were registered. The overall incidence was 0·4/1000 live births. Most infants (73%) had early-onset GBS infection with 53% registered within the first day. Serotype III predominated (59%) with other serotypes as follows: Ia (16%), Ib (8%), NT (7%), II (6%), other serotypes (5%). Recurrence of GBS infection was registered in six infants, and the interval with no antibiotic therapy varied from 2 to 39 days. The serotypes of the isolates obtained from first and second episodes were identical (serotype III in five, and serotype Ia in one infant). Paired isolates were indistinguishable by PFGE and antibiotic susceptibility testing. Invasive GBS infections in infants are still a problem in Denmark, and recurrent infections are registered in 1% of these infants.

Type
Research Article
Information
Epidemiology & Infection , Volume 132 , Issue 6 , December 2004 , pp. 1083 - 1090
Copyright
© 2004 Cambridge University Press