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Gentamicin-resistant staphylococei: genetics of an outbreak in a dermatology department

Published online by Cambridge University Press:  19 October 2009

Jay Naidoo ,
W. C. Noble ,
A. Weissmann  and
K. G. H. Dyke
Jay Naidoo
Affiliation:
Institute of Dermatology, University of London
W. C. Noble
Affiliation:
Institute of Dermatology, University of London
A. Weissmann
Affiliation:
Department of Dermatology, University of Munich
K. G. H. Dyke
Affiliation:
Department of Biochemistry, University of Oxford
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Summary

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The genetics of gentamicin resistance in Staphylococcus aureus strains isolated during an outbreak of infection in a dermatology department have been studied. The predominant strain of S. aureus did not appear to possess a plasmid mediating gentamicin resistance though one isolate yielded a plasmid coding for penicillin and gentamicin. Three distinct plasmids were isolated from other phage types of S. aureus which appeared towards the end of the epidemic. There appeared to be a stepwise loss of gentamicin resistance in the predominant strain.

Type
Research Article
Information
Journal of Hygiene , Volume 91 , Issue 1 , August 1983 , pp. 7 - 16
Copyright
Copyright © Cambridge University Press 1983

References

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