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Nutritional supplementation in Down syndrome: theoretical considerations and current status

Published online by Cambridge University Press:  01 March 2000

Cornelius Ani
Affiliation:
Centre for International Child Health, Institute of Child Health, University College London, London, UK.
Sally Grantham-McGregor
Affiliation:
Centre for International Child Health, Institute of Child Health, University College London, London, UK.
David Muller
Affiliation:
Biochemistry Unit, Institute of Child Health, University College London, London, UK.
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Abstract

Down syndrome (DS) is the most common inherited cause of learning disability, and affected individuals are more prone to infections, leukaemia, congenital heart disease and other anomalies, thyroid dysfunction, early senescence and Alzheimer's disease. These complications create a heavy burden for carers of individuals with DS and the social and health services. Consequently, any intervention that ameliorates some of these complications will have a significant impact on the quality of life of individuals with DS and their carers. However, before investing resources in interventions, it is important to ascertain their scientific validity.

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© 2000 Mac Keith Press

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