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A Selective Pattern of Neuropsychological Dysfunction in Patients With Panic Disorder-Agoraphobia

Published online by Cambridge University Press:  07 November 2014

Cristina Toni ,
Stefano Cappa ,
Giulio Perugi ,
Maura Boldrini ,
Franco Frare ,
Simone Pedri ,
Pierpaolo Medda  and
Giovanni B. Cassano
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Abstract

The neuropsychological performance of 19 unmedicated patients with panic disorder (PD) was compared with 15 age- and education-matched control subjects. The test results indicate a selective pattern of neuropsychological dysfunctions in patients with PD, suggestive of an involvement of the right frontal and temporoparietal brain areas.

Type
Grand Rounds
Information
CNS Spectrums , Volume 2 , Issue 9: Reflections on the Future of Neuroscience , October 1997 , pp. 64 - 67
Copyright
Copyright © Cambridge University Press 1997

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References

1.Roth, M, Harper, M. Temporal lobe epilepsy and the Phobic Anxiety-Depersonalization Syndrome, part II: practical and theoretical considerations. Compr Psychiatry. 1962;3:215–226.Google Scholar
2.Toni, C, Cassano, GB, Perugi, G, et al.Psychosensorial and related phenomena in panic disorder and in temporal lobe epilepsy. Compr Psychiatry. 1996;37:125–133.Google Scholar
3.Strian, F, Plogg, D. Anxiety related to central nervous system disfunction. In: Noyes, R, Roth, M, Burrows, GD, eds. Handbook of Anxiety, II. Amsterdam: Elsevier; 1988:431–475.Google Scholar
4.Fontaine, R, Breton, G, Dery, R, Fontaine, S, Elie, R. Temporal lobe abnormality in panic disorder: an MRI study. Biol Psychiatry. 1990;27:304–310.Google Scholar
5.Reiman, EM, Raichle, ME, Robins, E, et al.The application of positron emission tomography to the study of panic disorder. Am J Psychiatry. 1986;143:469–477.Google Scholar
6.Yeudall, LT, Schopflocher, D, Sussman, PS, et al.Panic attack syndrome with and without agoraphobia: neuropsychological and evoked potential correlates. In: Flor-Henry, P, Gruzelier, J eds. Laterality and Psychopatology. Amsterdam: Elsevier; 1983.Google Scholar
7.Lucas, JA, Telch, MJ, Bigler, ED. Memory functioning in panic disorder: a neuropsychological perspective. J Anxiety Disord. 1991;5:1–20.Google Scholar
8.Asmundson, GJG, Stein, MB, Larsen, DK, Walker, JR. Neurocognitive function in panic disorder and social phobia patients. Anxiety. 1995;1:201–207.Google Scholar
9.Keefe, SE. The contribution of neuropsychology to psychiatry. Am J Psychiatry. 1995;152:6–15.Google Scholar
10.Grafman, J, Jonas, B, Salazar, A. Wisconsin card sorting test performance based on location and size of neuroanatomical lesion in Vietnam veterans with penetrating head injury. Percept Mot Skills. 1990;71(3):1120–1122.CrossRefGoogle ScholarPubMed
11.Lezak, MD. Neuropsychological Assessment, 3rd ed. New York: Oxford University Press; 1995.Google Scholar
12.Gruzelier, J, Seymour, K, Wilson, L, Jolley, A, Hirsch, S. Impairments on neuropsychologic tests of temporohippocampal and frontohippocampal functions and word fluency in remitting schizophrenia and affective disorders. Arch Gen Psychiatry. 1988;45:623–629.Google Scholar
13.Khanna, S. Obsessive-compulsive disorder: is there a frontal lobe dysfunction? Biol Psychiatry. 1988;24:602–613.Google Scholar
14.Pillon, B. Troubles visuo-constructifs et méthodes de compensation: resultats de 85 patients atteints de lésions cérebrates. Neuropsychologia. 1981;19:375–383.Google Scholar
15.Milner, B. Psychological aspects of focal epilepsy and its neurological management. In: Purpura, DP, Penry, JK, Walter, RD eds. Advances in Neurology, vol. 8. New York: Raven Press: 1975.Google Scholar
16.McCaffrey, RJ, Rapee, RM, Gansler, DA, Barlow, DH. Interaction of neuropsychological and psychological factors in two cases of “space phobia”. J Behav Ther Experim Psychiatry. 1990;21:113–120.Google Scholar
17.Zielinski, CV, Taylor, MA, Juzwin, KR. Neuropsychological deficits in obsessive compulsive disorder. Neuropsych. Neuropsychol. Behav. Neurol. 1991;4:110–126.Google Scholar
18.Hollander, E, Decaria, C, Trungold, S, et al.Neuropsychiatric impairment in social phobia. Presented at the 145th American Psychiatric Association annual meeting; 1992; Washington, D.C.: NR 496:168–169.Google Scholar
19.Hermann, BP, Wyler, AR, Richely, ET, Rea, JM. Memory function and verbal learning ability in patients with complex partial seizure of temporal lobe origin. Epilepsia. 1987;28:547–554.Google Scholar
20.Giovagnoli, AR, Piazzini, A. The neuropsychological approach in patients with partial epilepsy: towards the identification of the most appropriate testing methods for clinical purposes. Epilepsia. 1995;89:7–10.Google Scholar