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Seizure Types, Epilepsy Syndromes, Etiology, and Diagnosis

Published online by Cambridge University Press:  07 November 2014

Abstract

The clinical manifestation of epileptic seizures may vary widely from patient to patient, depending on the region of the brain involved. Over the centuries, many seizure classific systems have been used, and the current most widely used classification system is that of the International League Against Epilepsy (ILAE). The ILAE system divides seizures into those of partial onset and those of generalized onset, depending on whether the initial clinical manifestations indicate that one cortical region or both hemispheres are involved at the onset of the seizure. Partial seizures are then divided into simple partial seizures, in which a fully conscious state is retained, or complex partial seizures, in which consciousness is impaired. A more recent classification system based purely on symptom features and signs has been proposed, and this system may provide advantages for localization, and especially for surgical evaluation. Epilepsy is a condition characterized by recurrent unprovoked seizures. Epilepsy may be idiopathic, cryptogenic, or symptomatic. Idiopathic epilepsies are generally genetic, and while man such syndromes have been described, advances in molecular genetics will undoubtedly reveal many more syndromes in near future. Cryptogenic epilepsies are those in which an underlying cause is suspected, but the etiology remains undetected. Epilepsies for which there is an underlying structural cause or major metabolic derangement are considered symptomatic. Common causes and diagnostic evaluation are described in this article.

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Copyright
Copyright © Cambridge University Press 2001

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References

1. Bancaud, J, Henriksen, O, Rubio-Donnadieu, F et al. , Proposal for revised clinical and eleotroencephalographic classification of epileptic seizures. Epilepsia. 1981;22:489501.Google Scholar
2. Engel, J JrJr. Editorial commentary:Classification of epileptic disorders [editorial commentary]. Epilepsia. 2001;42:316.CrossRefGoogle Scholar
3. Penfield, W, Perot, P. The brain's record of auditory and visual experience: a final summary and discussion. Brain. 1963;86:595696.CrossRefGoogle ScholarPubMed
4. Lüders, H, Acharya, J, Baumgarter, C et al. , Semiological seizure classification. Epilepsia. 1998;39:10061013.CrossRefGoogle ScholarPubMed
5. Lüders, HO, Burgess, R, Noachtar, S. Expanding the international classification of seizures to provide localization information. Neurology. 1993;43:16501655.CrossRefGoogle ScholarPubMed
6. Parra, J, Augustijn, PB, Geerts, Y et al. , Classification of epileptic seizures: a comparison of two systems. Epilepsia. 2001;42:476482.CrossRefGoogle ScholarPubMed
7. Commission on classification and terminology of the international league against epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia. 1989;30:389399.CrossRefGoogle Scholar
8. Lüders, H, Lesser, RP, Dinner, DS, Morris, HH. Benign focal epilepsy of childhood. In: Lüders, H, Lesser, RP, eds. Electroclinical Syndromes. New York, NY: Springer-Verlag; 1987:303346.CrossRefGoogle Scholar
9. Lerman, P, Kivity, S. Benign focal epilepsy of childhood. Arch Neurol. 1975;32:261264.CrossRefGoogle ScholarPubMed
10. Berkovic, SF, Howell, RA, Hopper, JL. Familial temporal lobe epilepsy: a new syndrome with adolescent/adult onset and a benign course. In: Wolf, P, ed. Epileptic Seizures and Syndromes. London, England: John Libbey; 1994:257263.Google Scholar
11. Berkovic, SF, McIntosh, AM, Howell, RA et al. , Familial temporal lobe epilepsy: a common disorder identified in twins. Ann Neurol. 1996;40:227235.CrossRefGoogle ScholarPubMed
12. Scheffer, IE, Bhatia, KP, Lopes-Cendes, I et al. , Autosomal dominant frontal epilespy misdiagnosed as sleep disorder. Lancet. 1994;343:515517.CrossRefGoogle Scholar
13. Scheffer, IE, Bhatia, KP, Lopes-Cendes, I et al. , Autosomal dominant nocturnal frontal epilepsy: a distinctive clinical disorder. Brain. 1995;118:6173.CrossRefGoogle ScholarPubMed
14. Semah, F, Picot, M-C, Adam, C et al. , Is the underlying cause of epilepsy a major prognostic factor for recurrence? Neurology. 1998;51:12561262.CrossRefGoogle Scholar
15. Stephen, LJ, Kwan, P, Brodie, M. Does the cause of localisation-related epilepsy influence the response to antiepileptic drug treatment? Epilepsia. 2001;42:357362.CrossRefGoogle ScholarPubMed
16. Boouma, PAD, Westendorp, RGJ, Van Dijk, JG et al. , The outcome of absence epilepsy: a meta-analysis. Neurology. 1996;47:802808.CrossRefGoogle Scholar
17. Andermann, F, Berkovic, S. Idiopathic generalized epilepsy with generalized and other seizures in adolescence. Epilepsia. 2001;42:317320.CrossRefGoogle ScholarPubMed
18. Hauser, WA, Annegers, JF, Kurland, LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935–1984. Epilepsia. 1994;34:453468.CrossRefGoogle Scholar
19. Hauser, WA, Annegers, JF, Kurland, LT. The prevalence of epilepsy in Rochester, Minnesota, 1940–1980. Epilepsia. 1991;32:429445.CrossRefGoogle Scholar
20. Wyllie, E, Comair, YG, Kotagal, et al. , Seizure outcome after epilepsy surgery in children and adolescents. Ann Neurol. 1998;44:740748.CrossRefGoogle ScholarPubMed
21. Edwards, JC, Wyllie, E, Ruggeri, PM et al. , Seizure outcome after surgery for epilepsy due to malformation of cortical development. Neurology. 2000;55:11101114.CrossRefGoogle ScholarPubMed
22. Bergin, PS, Fish, DR, Shorvon, SD et al. , Magnetic resonance imaging in partial epilepsy: additional abnormalities shown with the fluid-attenuated inversion recovery (FLAIR) pulse sequence. J Neurol Neurosurg Psychiatry. 1955;58:439443.CrossRefGoogle Scholar
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