Hostname: page-component-76fb5796d-2lccl Total loading time: 0 Render date: 2024-04-25T16:06:57.935Z Has data issue: false hasContentIssue false
  • English
  • Français

Morphometric study of the oval fossa in fetal and neonatal hearts

Published online by Cambridge University Press:  19 August 2008

Luis Alvarez ,
Antonia Aránega ,
Juan A. Marchal ,
María J. Hernández ,
Juan E. Fernández  and
Amanda R. González
Luis Alvarez*
Affiliation:
From the Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, Granada
Antonia Aránega
Affiliation:
From the Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, Granada
Juan A. Marchal
Affiliation:
From the Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, Granada
María J. Hernández
Affiliation:
From the Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, Granada
Juan E. Fernández
Affiliation:
From the Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, Granada
Amanda R. González
Affiliation:
From the Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, Granada
*
Prof. Luis Alvarez, Sección de Investigatión Básics Cardiovascular, Departamento de Ciencias Morfológicas, Facultad de Medicina, Universidad de Granada, Avda. de Madrid 11, E-18071 Granada, Spain. Tel. 34-58-243534; Fax. 34-58-243535.
Get access Rights & Permissions [Opens in a new window]

Abstract

Microdissection of the oval fossa from its right and left atrial aspects showed that the rim of the fossa was formed from an infolding of the atrial wall, which began between the base of the superior caval vein and the insertion of the right pulmonary vein to the left atrium. Because the rim varied in shape from circular to oval, we used morphometric methods to obtain patterns of normality of the diameters of the oval fossa, oval foramen, and the area of right and left atrial aspects of the septum. These values were found to correlate with log fetal and neonatal weight. Due to technical advances in prenatal diagnosis, these structures can now be examined in fetal life. Therefore, our morphometric data, when appropriately interpreted, have immediate clinical and surgical applications in the treatment of fetal and neonatal cardiovascular disorders.

Keywords

Human neonatal and fetal heartoval fossaquantitative anatomy
Type
Original Manuscripts
Information
Cardiology in the Young , Volume 5 , Issue 3 , July 1995 , pp. 257 - 261
Copyright
Copyright © Cambridge University Press 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Wilson, AD, Rao, PS, Alschlimann, S. Normal fetal foramen flap and transatrial Doppler velocity pattern. J Am Soc Echocardiol 1990; 3: 491–494.CrossRefGoogle ScholarPubMed
2.Naeye, RL, Blanc, WA. Prenatal narrowing or closure of the foramen ovale. Circulation 1964; 30: 736–742.CrossRefGoogle ScholarPubMed
3.Fouron, JC. Physiologie cardio-vasculaire foetale. In: Pourcelot, L (ed). Dynamique Cardio-vasculaire Foetale et Neonatale. Echocardiographie-Doppler. Masson, Paris, 1991, pp 67–72.Google Scholar
4.Rocchini, AP. Transcatheter closure of atrial septal defects. Past, present and future. Circulation 1990; 82: 1044–1045.CrossRefGoogle ScholarPubMed
5.Ferreira, SMAG, Yen Ho, S, Anderson, RH. Morphological study of defects of the atrial septum within the oval fossa: implications for transcatheter closure of left-to-right shunt. Brit Heart J 1992; 67: 316–320.CrossRefGoogle ScholarPubMed
6.Atkins, DL, Clark, EB, Marvin, W. Foramen ovale/atrial septum area ratio: a marker of transatrial blood flow. Circulation 1982; 66: 281–283.CrossRefGoogle ScholarPubMed
7.Hutchins, GM, Moore, GW, Jones, JF, Miller, ST. Postnatal endocardial fibroelastosis of the valve of the foramen ovale. Am J Cardiol 1981; 47: 90–94.CrossRefGoogle ScholarPubMed
8.Sutherland, GR, Roelandt, JRTC, Fraser, AG, Anderson, RH. Transesophageal Echocardiography in Clinical Practice. Gower Medical, London, 1991, pp 3.14–3.15.Google Scholar
9.Lev, M, Arcilla, R, Rimoldi, HJ, Lieata, RM, Gasul, BM. Premature narrowing or closure of the foramen ovale. Am Heart J 1963; 65: 638–641.CrossRefGoogle ScholarPubMed
10.Topaz, O, Feigl, A, Edwards, JE. Aneurysm of the fossa ovalis in infants: a pathological study. Pediatr Cardiol 1985; 6: 65–68.CrossRefGoogle Scholar
11.Chan, KG, Godman, MJ. Morphological variations of fossa ovalis atrial septal defects (secundum): feasibility for transcutaneous closure with the clam-shell device. Brit Heart J 1993; 69: 52–55.CrossRefGoogle ScholarPubMed
12.Perry St, B, Van der Velde, ME, Bridges, ND, Keane, JF, Lock, JE. Transcatheter closure of atrial and ventricular septal defects. Herz 1993; 18: 135–141.Google Scholar
13.Hellenbrand, WE, Fahey, JT, McGowan, FX, Weltin, GG, Kleinman, CS. Transesophageal echocardiographic guidance of transcatheter closure of atrial septal defect. Am J Cardiol 1990; 66: 207–213.CrossRefGoogle ScholarPubMed
14.Rome, JJ, Keane, JF, Perry, SB, Spevak, PJ, Lock, JE. Double umbrella closure of atrial defects. Initial clinical applications. Circulation 1990; 82: 751–758.CrossRefGoogle ScholarPubMed
15.Anderson, RH, Macartney, FH, Shinebourne, EA, Tynan, M. Paediatric Cardiology, Volume 1. Churchill Livingstone, Edinburgh, 1987, pp 541–562.Google Scholar