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Management of a child with pulmonary arterial hypertension presenting with systemic hypertension

Published online by Cambridge University Press:  17 June 2015

Saul Flores ,
Joshua Daily ,
Jayant “Nick” Pratap ,
Michelle C. Cash  and
Russel Hirsch
Saul Flores*
Affiliation:
Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
Joshua Daily
Affiliation:
Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
Jayant “Nick” Pratap
Affiliation:
Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America Department of Anesthesia, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
Michelle C. Cash
Affiliation:
Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
Russel Hirsch
Affiliation:
Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
*
Correspondence to: S. Flores, Heart Institute, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, United States of America. Tel: 513 803 3124; Fax: 513-636-3952; E-mail: saul.flores@cchmc.org
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Abstract

We describe the course and management of a 12-year-old girl with severe pulmonary arterial hypertension who initially presented with severe systemic hypertension. Successful therapy included pulmonary vasodilators and an atrial septostomy, while ensuring adequate maintenance of her systemic vascular resistance to maintain cardiac output. Clear understanding of the physiology and judicious medical management in patients with severe pulmonary arterial hypertension using extreme compensatory mechanisms is vitally important.

Keywords

Pulmonary arterial hypertensionsystemic hypertensionpaediatrics
Type
Brief Reports
Information
Cardiology in the Young , Volume 26 , Issue 2 , February 2016 , pp. 378 - 381
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Copyright
© Cambridge University Press 2015 

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References

1. Berger, RM, Beghetti, M, Humpl, T, et al. Clinical features of paediatric pulmonary hypertension: a registry study. Lancet 2012; 379: 537–546.Google Scholar
2. Mallory, GB Jr, Hanna, BD, Ivy, DD, Shardonofsky, F, Farber, HJ. Management and controversies in pediatric pulmonary hypertension. Pediatr Allergy Immunol Pulmonol 2011; 22: 139–150.CrossRefGoogle Scholar
3. Gomberg-Maitland, M, Bull, TM, Saggar, R, et al. New trial designs and potential therapies for pulmonary artery hypertension. J Am Coll Cardiol 2013; 62: D82–D91.CrossRefGoogle ScholarPubMed
4. Simonneau, G, Gatzoulis, MA, Adatia, I, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2013; 62.CrossRefGoogle ScholarPubMed
5. McLaughlin, VV, Shillington, A, Rich, S. Survival in primary pulmonary hypertension the impact of epoprostenol therapy. Circulation 2002; 106: 1477–1482.Google Scholar
6. Sitbon, O, Humbert, M, Nunes, H, et al. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension Prognostic factors and survival. J Am Coll Cardiol 2002; 40: 780–788.Google Scholar