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Left ventricular thrombus in multisystem inflammatory syndrome in children associated with COVID-19

Part of: Advanced Imaging

Published online by Cambridge University Press:  04 June 2021

Jakob Schroder Open the ORCID record for Jakob Schroder [Opens in a new window] ,
Morten Asp Vonsild Lund ,
Niels Vejlstrup ,
Klaus Juul  and
Ulrikka Nygaard
Jakob Schroder*
Affiliation:
Department of Pediatric Cardiology, Rigshospitalet, University of Copenhagen, Blegdamsvej, Denmark
Morten Asp Vonsild Lund
Affiliation:
Department of Cardiology, Rigshospitalet, University of Copenhagen, Blegdamsvej, Denmark
Niels Vejlstrup
Affiliation:
Department of Cardiology, Rigshospitalet, University of Copenhagen, Blegdamsvej, Denmark
Klaus Juul
Affiliation:
Department of Pediatric Cardiology, Rigshospitalet, University of Copenhagen, Blegdamsvej, Denmark
Ulrikka Nygaard
Affiliation:
Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Blegdamsvej, Denmark
*
Author for correspondence: Jakob Schroder, MD, PhD, Department of Pediatric Cardiology, Rigshospitalet, University of Copenhagen, Blegdamsvej, Denmark. Tel: +45 23820896. E-mail: jakob.arnborg.schroeder.02@regionh.dk
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Abstract

A 17-year-old adolescent with severe multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease-2019 developed reduced left ventricular function and left ventricular thrombus. With treatment, his condition improved and the thrombus was dissolved. This case illustrates the risk of severe intra-cardiac thrombotic complications in patients with MIS-C.

Keywords

thrombusautoimmuneechocardiographyhaemodynamicscardiac magnetic resonance
Type
Brief Report
Information
Cardiology in the Young , Volume 32 , Issue 1 , January 2022 , pp. 138 - 141
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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References

Belay, ED, Abrams, J, Oster, ME, et al. Trends in geographic and temporal distribution of US children with multisystem inflammatory syndrome during the COVID-19 pandemic. JAMA Pediatr 2021; 30333: 1–9.Google Scholar
Feldstein, LR, Tenforde, MW, Friedman, KG, et al. Characteristics and outcomes of US children and adolescents with multisystem inflammatory syndrome in children (MIS-C) compared with severe acute COVID-19. JAMA 2021; 02115: 1–14.Google Scholar
Feldstein, LR, Rose, EB, Horwitz, SM, et al. Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med 2020; 383: 334–346.CrossRefGoogle ScholarPubMed
Minen, F, Hands, C, Mustafa, MR, Pienaar, A, Lillie, J. Thrombophilia in pediatric patients with multisystem inflammatory syndrome in children secondary to Coronavirus disease 2019 Supported on Extracorporeal Membrane Oxygenation. ASAIO J 2021; 67: 7–11.CrossRefGoogle ScholarPubMed
Henderson, LA, Canna, SW, Friedman, KG, et al. American college of rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARS–CoV-2 and hyperinflammation in pediatric COVID-19: version 1. Arthritis Rheumatol 2020; 72: 1791–1805.CrossRefGoogle ScholarPubMed
Goldenberg, NA, Sochet, A, Albisetti, M, et al. Consensus-based clinical recommendations and research priorities for anticoagulant thromboprophylaxis in children hospitalized for COVID-19–related illness. J Thromb Haemostasis 2020; 18: 3099–3105.CrossRefGoogle ScholarPubMed
Connors, JM, Levy, JH. Thromboinflammation and the hypercoagulability of COVID-19. J Thromb Haemostasis 2020; 18: 1559–1561.CrossRefGoogle ScholarPubMed
Black, IW, Chesterman, CN, Hopkins, AP, Lee, LCL, Chong, BH, Walsh, WF. Hematologic correlates of left atrial spontaneous echo contrast and thromboembolism in nonvalvular atrial fibrillation. J Am Coll Cardiol 1993; 21: 451–457.CrossRefGoogle ScholarPubMed
Matsubara, D, Kauffman, HL, Wang, Y, et al. Echocardiographic findings in pediatric multisystem inflammatory syndrome associated with COVID-19 in the United States. J Am Coll Cardiol 2020; 76: 1947–1961.CrossRefGoogle ScholarPubMed
Theocharis, P, Wong, J, Pushparajah, K, et al. Multimodality cardiac evaluation in children and young adults with multisystem inflammation associated with COVID-19. Eur Heart J – Cardiovasc Imaging 2020: 1–8.CrossRefGoogle Scholar

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