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Hypotension within 1 week of life associated with poor short- and long-term outcomes in very low birth weight infants

Published online by Cambridge University Press:  02 July 2018

Tae-Hoon Kim ,
Cheong-Jun Moon ,
In K. Sung  and
Young A. Youn
Tae-Hoon Kim
Affiliation:
Department of Cardiology, Cardiovascular Center and Cardiology Division, New Korea Hospital, Gimpo-si, Gyeonggi-do, Republic of Korea
Cheong-Jun Moon
Affiliation:
Department of Pediatrics, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
In K. Sung
Affiliation:
Department of Pediatrics, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Young A. Youn*
Affiliation:
Department of Pediatrics, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
*
Author for correspondence: Y. A. Youn, Department of Pediatrics, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea. Tel: +82 10 8760 9597; Fax: +82 2 537 4544; E-mail: lea732@hanmail.net
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Abstract

We examined whether hypotension in very low birth weight infants aged⩽1 week was associated with hospital morbidities and overall mortality. Further, we studied whether hypotension was associated with poor neurodevelopmental outcomes in these patients at the corrected age of 18 months. A total of 166 very low birth weight infants were studied during this period. Hospital outcomes and neurodevelopmental outcomes at the corrected age of 18 months were evaluated. Among the 166 very low birth weight infants, 95 patients (57.2%) experienced hypotension at⩽1 week and were associated with an increased incidence of morbidities and mortality. At the corrected age of 18 months, hypotension of the⩽1 week group had significantly lower scores in all three – cognitive, language, and motor – composites of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) screening tests. In addition, a multivariable logistic regression analysis showed that longer mechanical ventilation and periventricular leukomalacia were additionally associated with worse cognitive and language neurodevelopmental outcomes. Hypotension in very low birth weight infants within 1 week of life was associated with increased morbidities and overall mortality. It was also associated with an increased risk of cognitive and language outcomes.

Keywords

Hypotensionoutcomesmorbiditylong term
Type
Original Article
Information
Cardiology in the Young , Volume 28 , Issue 8 , August 2018 , pp. 1037 - 1041
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Copyright
© Cambridge University Press 2018 

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Footnotes

Cite this article: Kim T-H, Moon C-J, Sung IK, Youn YA. (2018) Hypotension within 1 week of life associated with poor short- and long-term outcomes in very low birth weight infants. Cardiology in the Young28: 1037–1041. doi: 10.1017/S1047951118000732

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