Skip to main content Accessibility help
×
Home
Hostname: page-component-55597f9d44-l69ms Total loading time: 0.411 Render date: 2022-08-08T08:23:40.716Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "useRatesEcommerce": false, "useNewApi": true } hasContentIssue true

Early presentation of endomyocardial fibrosis

Published online by Cambridge University Press:  19 April 2011

Vera D. Aiello*
Affiliation:
Laboratory of Pathology, Heart Institute (InCor) of São Paulo University Medical School, São Paulo, Brazil
Marcelo B. Jatene
Affiliation:
Pediatric Cardiac Surgery Division, Heart Institute (InCor) of São Paulo University Medical School, São Paulo, Brazil
*
Correspondence to: V. D. Aiello, Laboratory of Pathology, Heart Institute (InCor), University of Sao Paulo School of Medicine, Av. Dr. Eneas C. Aguiar, 44, Sao Paulo 05403-000, Brazil. Tel: +55 11 3069–5252; Fax: +55 11 3069–5279; E-mail: Vera.Aiello@incor.usp.br
Rights & Permissions[Opens in a new window]

Abstract

Type
Letters to the Editor
Copyright
Copyright © Cambridge University Press 2011

Dear Dr Baker,

Having read the interesting report by Cilliers et al about a patient with early presentation of endomyocardial fibrosis at the age of 22 months,Reference Cilliers, Adams and Mocumbi1 we would like to make some comments in comparison with one case we reported some years ago.Reference Jatene, Contreras and Lameda2 Certainly, Cilliers’ case is one of the youngest already reported in the literature. They state that the youngest patient reported was an 18-month-old baby who had the diagnosis based on echocardiographic findings.Reference Saraçlar, Ozer, Oztunç and Celiker3 However, our patient was younger (a 4-month-old Caucasian baby) and we also provided histological confirmation of the disease. In fact, we believe that our patient presented the cardiac lesions since birth, although they were not clinically recognised at that time. The north-eastern region of Brazil, like some African countries, is considered an endemic area for endomyocardial fibrosis, but neither the baby nor his parents were originally from that area. Additional features in our case were the existence of Rh incompatibility between the mother and foetus and treated hypothyroidism in the mother.

We agree with the authors regarding a possible genetic link in the aetiology of the disease, but we additionally believe that congenital development of the cardiac lesions may exist. The study of these ‘extremely early’ presentation forms may help in the understanding of the pathogenetic mechanisms of endomyocardial fibrosis, which are still not completely understood.

References

1.Cilliers, AM, Adams, PE, Mocumbi, AO. Early presentation of endomyocardial fibrosis in a 22-month-old child: a case report. Cardiol Young 2011; 21: 101103.CrossRefGoogle Scholar
2.Jatene, MB, Contreras, IS, Lameda, LC, et al. Endomyocardial fibrosis in infancy. Arq Bras Cardiol 2003; 80: 438445.CrossRefGoogle ScholarPubMed
3.Saraçlar, M, Ozer, S, Oztunç, F, Celiker, A. Echocardiographic findings in endomyocardial fibrosis. Turk J Pediatr 1992; 32: 4753.Google Scholar
You have Access
1
Cited by

Save article to Kindle

To save this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Early presentation of endomyocardial fibrosis
Available formats
×

Save article to Dropbox

To save this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about saving content to Dropbox.

Early presentation of endomyocardial fibrosis
Available formats
×

Save article to Google Drive

To save this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about saving content to Google Drive.

Early presentation of endomyocardial fibrosis
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *