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Cardiovascular events in perimembranous ventricular septal defect with left ventricular volume overload: a French prospective cohort study (FRANCISCO)

Published online by Cambridge University Press:  23 September 2021

Lisa Guirgis
Affiliation:
Department of Pediatric and Adult Congenital Heart Diseases, Marie Lannelongue Hospital, Groupe Hospitalier Paris Saint-Joseph, centre de reference cardiopathies congénitales complexes M3C, université Paris-Sud, Le Plessis-Robinson, France
Estibaliz Valdeolmillos
Affiliation:
Department of Pediatric Cardiology, Centre Hospitalier Universitaire Haut Leveque, centre de reference cardiopathies congénitales complexes M3C, IHU Lyric, Bordeaux, France
Guy Vaksmann
Affiliation:
Department of Pediatric Cardiology, Private hospital La Louvière, Lille, France
Clément Karsenty
Affiliation:
Department of Pediatric Cardiology, centre de compétence M3C, Centre Hospitalier Universitaire de Toulouse, Toulouse, France
Ali Houeijeh
Affiliation:
Department of Pediatric Cardiology, centre de compétence M3C, Centre Hospitalier Universitaire de Lille, Lille, France
Eric Hery
Affiliation:
Department of Cardiology, Centre Hospitalier Privé Sainte Marie, Osny, France
Pascal Amedro
Affiliation:
Department of Paediatric and Congenital Cardiology, M3C Regional Reference Centre, Montpellier University Hospital, PhyMedExp, INSERM, CNRS, Montpellier, France
Nicolas Pangaud
Affiliation:
Department of Pediatric Cardiology, Clinique du Val d’Ouest, Lyon, France
Nadir Benbrik
Affiliation:
Department of Pediatric Cardiology and Pediatric Cardiac Surgery, centre de compétence M3C, Centre Hospitalier Universitaire de Nantes, institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France
Carine Vastel
Affiliation:
Department of Pediatric Cardiology, Centre de spécialités pédiatriques de l’est parisien, Créteil, France
Antoine Legendre
Affiliation:
Department of Adult Congenital Heart Disease, centre de reference M3C, Hospital Europen Georges Pompidou, Paris, France
Zakaria Jalal
Affiliation:
Department of Pediatric Cardiology, Centre Hospitalier Universitaire Haut Leveque, centre de reference cardiopathies congénitales complexes M3C, IHU Lyric, Bordeaux, France
Khaled Hadeed
Affiliation:
Department of Pediatric Cardiology, centre de compétence M3C, Centre Hospitalier Universitaire de Toulouse, Toulouse, France
Magalie Ladouceur
Affiliation:
Department of Adult Congenital Heart Disease, centre de reference M3C, Hospital Europen Georges Pompidou, Paris, France
Laurence Iserin
Affiliation:
Department of Adult Congenital Heart Disease, centre de reference M3C, Hospital Europen Georges Pompidou, Paris, France
Daniela Laux
Affiliation:
Department of Pediatric and Adult Congenital Cardiology, UE3C Lowendal, Paris, France
Xavier Iriart
Affiliation:
Department of Pediatric Cardiology, Centre Hospitalier Universitaire Haut Leveque, centre de reference cardiopathies congénitales complexes M3C, IHU Lyric, Bordeaux, France
Karine Warin Fresse
Affiliation:
Department of Pediatric Cardiology and Pediatric Cardiac Surgery, centre de compétence M3C, Centre Hospitalier Universitaire de Nantes, institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France
Bertrand Leobon
Affiliation:
Department of Pediatric Cardiology, centre de compétence M3C, Centre Hospitalier Universitaire de Toulouse, Toulouse, France
Samir Harchaoui
Affiliation:
Department of Pediatric and Adult Congenital Cardiology, Lisieux, France
Virginie Lambert
Affiliation:
Department of Pediatric and Adult Congenital Cardiology, Institut Mutualiste Montsouris, Paris, France
Ronan Bonefoy
Affiliation:
Department of Pediatric Cardiology, Hopital Robert Debré, Paris, France
Adeline Basquin
Affiliation:
Department of Pediatric Cardiology, Rennes, France
Aurélie Chalard
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire Gabriel Montpied, Clermont Ferrand, France
Stéphanie Douchin
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France
Ivan Bouzguenda
Affiliation:
Department of Pediatric Cardiology, Private hospital La Louvière, Lille, France
Charlotte Denis
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire Dijon, Dijon, France
Hugues Lucron
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Hopital Pierre Zobda Quitman Fort de France, Martinique, France
Gilles Bosser
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Hopital Brabois, Vandoeuvre Les Nancy, France
Elise Barre
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire Charles Nicolle, Rouen, France
Bérangère Urbina-Hiel
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire Amiens, Amiens, France
Pauline Helms
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France
Hélène Ansquer
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Régional Universitaire Morvan de Brest, Brest, France
Quentin Hauet
Affiliation:
Department of Pediatric Cardiology and Pediatric Cardiac Surgery, centre de compétence M3C, Centre Hospitalier Universitaire de Nantes, institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France
Anne-Sophie Leborgne
Affiliation:
Department of Pediatric Cardiology, Centre Hospitalier Yves le Foll, St Brieuc, France
Laurence Cohen
Affiliation:
Pediatric Cardiology, Massy, France
Jean Marc Lupoglazoff
Affiliation:
Centre Cardiologique du Nord, St Denis, France
Maurice Guirgis
Affiliation:
Department of Pediatric Cardiology, Polyclinique la Roseraie, Aubervilliers, France
Céline Gronier
Affiliation:
Department of Pediatric Cardiology and Pediatric Cardiac Surgery, centre de compétence M3C, Centre Hospitalier Universitaire de Nantes, institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France
Pascale Maragnes
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire Cote de Nacre, Caen, France
Pamela Moceri
Affiliation:
Department of Pediatric and Adult Cardiology, Centre Hospitalier Universitaire Lenval, centre de competence M3C UR2CA, Université Côte d’Azur, CHU de Nice, Nice, France
Pierre Mauran
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, American Memorial Hospital, Reims, France
Claire Bertail
Affiliation:
Department of Pediatric Cardiology, entre de competence M3C, hospices civils de Lyon, Centre Hospitalier Universitaire Louis Pradel de Bron, Lyon, France
Bruno Lefort
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Centre Hospitalier Universitaire, Tours, France
François Godart
Affiliation:
Department of Pediatric Cardiology, centre de compétence M3C, Centre Hospitalier Universitaire de Lille, Lille, France
Alban-Elouen Baruteau
Affiliation:
Department of Pediatric Cardiology and Pediatric Cardiac Surgery, centre de compétence M3C, Centre Hospitalier Universitaire de Nantes, institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France
Caroline Ovaert
Affiliation:
Department of Pediatric Cardiology, centre de competence M3C, Assistance Publique des Hopitaux de Marseille, Centre Hospitalier Universitaire La Timone, Marseille, France
Damien Bonnet
Affiliation:
Department of Pediatric Cardiology, centre coordinateur reseau M3C, Assistance Publique des Hopitaux de Paris, Necker Enfants Malades Hospital, Paris, France
Nicolas Combes
Affiliation:
Department of Pediatric Cardiology, Clinique Pasteur, Toulouse, France
Diala Khraiche
Affiliation:
Department of Pediatric Cardiology, centre coordinateur reseau M3C, Assistance Publique des Hopitaux de Paris, Necker Enfants Malades Hospital, Paris, France
Lucile Houyel
Affiliation:
Department of Pediatric Cardiology, centre coordinateur reseau M3C, Assistance Publique des Hopitaux de Paris, Necker Enfants Malades Hospital, Paris, France
Jean Benoit Thambo
Affiliation:
Department of Pediatric Cardiology, Centre Hospitalier Universitaire Haut Leveque, centre de reference cardiopathies congénitales complexes M3C, IHU Lyric, Bordeaux, France
Meriem Mostefa-Kara
Affiliation:
Department of Pediatric and Adult Congenital Heart Diseases, Marie Lannelongue Hospital, Groupe Hospitalier Paris Saint-Joseph, centre de reference cardiopathies congénitales complexes M3C, université Paris-Sud, Le Plessis-Robinson, France
Sébastien Hascoet*
Affiliation:
Department of Pediatric and Adult Congenital Heart Diseases, Marie Lannelongue Hospital, Groupe Hospitalier Paris Saint-Joseph, centre de reference cardiopathies congénitales complexes M3C, université Paris-Sud, Le Plessis-Robinson, France
*
Author for correspondence: Sebastien Hascoet, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint-Joseph, 133 avenue de la Résistance 92350 Le Plessis-Robinson, France. Tel: +33 140 942 800. E-mail: s.hascoet@ghpsj.fr

Brief summary

The long-term prospective multi-centre nationwide (French) observational study FRANCISCO will provide new information on perimembranous ventricular septal defect with left ventricular overload but no pulmonary hypertension in children older than 1 year. Outcomes will be compared according to treatment strategy (watchful waiting, surgical closure, or percutaneous closure) and anatomic features of the defect. The results are expected to provide additional guidance about the optimal treatment of this specific population, which is unclear at present.

Type
Review
Copyright
© The Author(s), 2021. Published by Cambridge University Press

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